Detection of Kawasaki disease-associated antigen in inflamed gastrointestinal tract in acute Kawasaki disease

被引:4
|
作者
Miura, M [1 ]
Garcia, FL
Crawford, SE
Rowley, AH
机构
[1] Northwestern Univ, Dept Pediat, Chicago, IL 60611 USA
[2] Northwestern Univ, Dept Pathol, Chicago, IL 60611 USA
[3] Childrens Mem Hosp, Chicago, IL 60614 USA
[4] Feinberg Sch Med, Chicago, IL USA
关键词
gastrointestinal tract; immunohistochemistry; Kawasaki disease; kidney; synthetic antibody;
D O I
10.1097/01.inf.0000180973.98862.50
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We performed immunohistochemistry experiments using synthetic antibodies on the gastrointestinal tract and kidney from acute Kawasaki disease patients. Significant gastrointestinal tract inflammation was present in only 2/7 patients, who had antigen detected at the site of inflammation. Antigen was not detected in kidney from 6 patients. The presence of antigen may be related to gastrointestinal pathology in acute Kawasaki disease.
引用
收藏
页码:927 / 929
页数:3
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