Association between interleukin-4 gene polymorphisms and intracerebral haemorrhage in Korean population

被引:6
|
作者
Park, H. J. [2 ]
Kim, M. J. [2 ]
Kang, S. W. [2 ]
Kim, S. K. [2 ]
Lee, J. S. [3 ]
Park, H. K. [3 ]
Yoo, S. D. [1 ]
Kim, D. H. [1 ]
Yun, D. H. [1 ]
Kim, H. S. [1 ]
Kim, J. W. [2 ]
Chung, J. H. [2 ]
Jeong, Y. S. [1 ]
机构
[1] Kyung Hee Univ, Sch Med, Dept Phys Med & Rehabil, Seoul 130701, South Korea
[2] Kyung Hee Univ, Sch Med, Kohwang Med Res Inst, Seoul 130701, South Korea
[3] Kyung Hee Univ, Sch Med, Dept Neuropsychiat & Emergency Med, Seoul 130701, South Korea
关键词
ISCHEMIC-STROKE; IL-4; RISK; EXPRESSION; CYTOKINES;
D O I
10.1111/j.1744-313X.2011.01010.x
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Interleukin-4 (IL4) polymorphisms (rs2243250, rs2070874) were analysed in Korean patients with ischaemic stroke (IS) (n = 119) and intracerebral haemorrhage (ICH) (n = 79), and age-matched controls (n = 267, IS; n = 401, ICH) using direct sequencing. Both single nucleotide polymorphisms and their haplotypes were associated with ICH, but not IS.
引用
收藏
页码:321 / 325
页数:5
相关论文
共 50 条
  • [1] Association between the polymorphisms of interleukin-4, the interleukin-4 receptor gene and asthma
    Zhu Ning
    Gong Yi
    Chen Xiao-dong
    Zhang Jing
    Long Feng
    He Jian
    Xia Jing-wen
    Dong Liang
    [J]. CHINESE MEDICAL JOURNAL, 2013, 126 (15) : 2943 - 2951
  • [2] Polymorphisms of interleukin-4 promoter and receptor gene for schizophrenia in the Korean population
    Jun, TY
    Lee, KU
    Pae, CU
    Chae, JH
    Bahk, WM
    Kim, KS
    Han, H
    [J]. PSYCHIATRY AND CLINICAL NEUROSCIENCES, 2003, 57 (03) : 283 - 288
  • [3] Association Between Paraoxonase Gene Polymorphisms and Intracerebral Hemorrhage in a Korean Population
    Hae Jeong Park
    Su Kang Kim
    Hyun-Kyung Park
    Joo-Ho Chung
    [J]. Journal of Molecular Neuroscience, 2015, 57 : 410 - 416
  • [4] Association Between Paraoxonase Gene Polymorphisms and Intracerebral Hemorrhage in a Korean Population
    Park, Hae Jeong
    Kim, Su Kang
    Park, Hyun-Kyung
    Chung, Joo-Ho
    [J]. JOURNAL OF MOLECULAR NEUROSCIENCE, 2015, 57 (03) : 410 - 416
  • [5] Association of single nucleotide polymorphisms in the interleukin-4 gene and interleukin-4 receptor gene with Crohn’s disease in a British population
    GP Aithal
    CP Day
    J Leathart
    AK Daly
    M Hudson
    [J]. Genes & Immunity, 2001, 2 : 44 - 47
  • [6] Association between interleukin-4 polymorphisms and asthma
    李亚斐
    郭波涛
    韩家信
    朱才众
    张耀
    马翔宇
    张路
    熊鸿燕
    [J]. Military Medical Research, 2007, (05) : 312 - 319
  • [7] Association of single nucleotide polymorphisms in the interleukin-4 gene and interleukin-4 receptor gene with Crohn's disease in a British population
    Aithal, GP
    Day, CP
    Leathart, J
    Daly, AK
    Hudson, M
    [J]. GENES AND IMMUNITY, 2001, 2 (01) : 44 - 47
  • [8] Two polymorphisms of interleukin-4 gene in Korean adult periodontitis
    Kang, BY
    Choi, YK
    Choi, WH
    Kim, KT
    Choi, SS
    Kim, K
    Ha, NJ
    [J]. ARCHIVES OF PHARMACAL RESEARCH, 2003, 26 (06) : 482 - 486
  • [9] Association Between Single Nucleotide Polymorphisms of the Interleukin-4 Gene and Atopic Dermatitis
    Gharagozlou, Mohammad
    Behniafard, Nasrin
    Amirzargar, Ali Akbar
    Hosseinverdi, Sima
    Sotoudeh, Soheila
    Farhadi, Elham
    Khaledi, Mojdeh
    Aryan, Zahra
    Moghaddam, Zahra Gholizadeh
    Mahmoudi, Maryam
    Aghamohammadi, Asghar
    Rezaei, Nima
    [J]. ACTA DERMATOVENEROLOGICA CROATICA, 2015, 23 (02) : 96 - 100
  • [10] Gene-gene interaction between interleukin-4 and interleukin-4 receptor α in Korean children with asthma
    Lee, SG
    Kim, BS
    Kim, JH
    Lee, SY
    Choi, SO
    Shim, JY
    Hong, TJ
    Hong, SJ
    [J]. CLINICAL AND EXPERIMENTAL ALLERGY, 2004, 34 (08): : 1202 - 1208