The platelet intracellular calcium response to serotonin in subsyndromal depression

被引：9
|
作者：
Berk, M [1 ]
Mitchell, VS [1 ]
Plein, H [1 ]
机构：
[1] Univ Witwatersrand, Sch Med, Dept Psychiat, ZA-2193 Johannesburg, South Africa
来源：
INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY | 1998年 / 13卷 / 03期
关键词：
platelet; depression; subsyndromal; serotonin; calcium; intracellular;
D O I：
10.1097/00004850-199805000-00002
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The relationship of subsyndromal depression to syndromal depression is unclear. Increased sensitivity of platelet serotonin type 2 receptor has been reported in depression using the Fura-2 technique. The sensitivity of the platelet serotonin type 2 receptor was assessed using the Fura-2 method in 16 patients with subsyndromal depression and 14 controls. The patient group had higher numerical values of both basal and serotonin-stimulated levels of platelet intracellular calcium that did not however reach statistical significance. Int Clin Psychopharmacol 13:107-110 (C) 1998 Lippincott-Raven Publishers.
引用
收藏
页码：107 / 110
页数：4
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