"An Extra Variable to Consider"-Vaccine-Induced Seropositivity and Adolescent HIV Vaccine Clinical Trials

被引：0
|
作者：
Fatola, Omolayo [1 ]
Corneli, Amy [2 ,3 ]
Perry, Brian [2 ]
Hanlen-Rosado, Emily [2 ]
Nsonwu, Adora [2 ]
Constantine, Evangelia P. [4 ]
Thompson, Amelia B. [5 ,6 ,7 ]
机构：
[1] Indiana Univ Sch Med, Indianapolis, IN 46202 USA
[2] Duke Univ, Dept Populat Hlth Sci, Sch Med, Durham, NC USA
[3] Duke Univ, Duke Clin Res Inst, Sch Med, Durham, NC USA
[4] Dartmouth Coll, Hanover, NH 03755 USA
[5] Duke Univ, Duke Human Vaccine Inst, Sch Med, Durham, NC USA
[6] Duke Univ, Dept Pediat, Div Infect Dis, Sch Med, Durham, NC USA
[7] AdventHlth Children, Div Infect Dis, Dept Pediat, Orlando, FL 32803 USA
来源：
JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY | 2022年 / 11卷 / 05期
关键词：
adolescent; HIV; prevention; vaccine; VISP;
D O I：
10.1093/jpids/piac001
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Our study explores the understanding of vaccine-induced seropositivity (VISP) and its potential impact on US adolescents' and caregivers' willingness to participate in adolescent HIV vaccine clinical trials. Findings from in-depth interviews suggest that addressing concerns about VISP will be essential for future pediatric HIV vaccine trials in the United States. Addressing adolescents' and their caregivers' concerns about vaccine-induced seropositivity will likely be essential to the success of future pediatric HIV vaccine trials in the United States.
引用
收藏
页码：221 / 224
页数：4
相关论文
共 50 条
  • [1] HIV vaccine-induced seropositivity common in clinical trials
    Reactions Weekly, 2010, 1312 (1) : 4 - 4
  • [2] Induction of Vaccine-Induced HIV Seropositivity in Preventative HIV Vaccine Trials
    Cooper, C. J.
    Wecker, M.
    Djomand, G.
    Metch, B.
    Dragavon, J.
    Coombs, R. W.
    Baden, L.
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 2008, 24 : 103 - 103
  • [3] Vaccine-Induced HIV Seropositivity/Reactivity in Noninfected HIV Vaccine Recipients
    Cooper, Cristine J.
    Metch, Barbara
    Dragavon, Joan
    Coombs, Robert W.
    Baden, Lindsey R.
    JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2010, 304 (03): : 275 - 283
  • [4] Vaccine-induced HIV seropositivity: A problem on the rise
    Van Braeckel, Eva
    Koutsoukos, Marguerite
    Bourguignon, Patricia
    Clement, Frederic
    McNally, Lisa
    Leroux-Roels, Geert
    JOURNAL OF CLINICAL VIROLOGY, 2011, 50 (04) : 334 - 337
  • [5] Long-term safety and vaccine-induced seropositivity in healthy volunteers from HIV vaccine trials
    Durier, Christine
    Desaint, Corinne
    Lelievre, Jean-Daniel
    Silbermann, Benjamin
    Pialoux, Gilles
    Cuzin, Lise
    Bonnet, Benedicte
    Poizot-Martin, Isabelle
    Bouakane, Amel
    Paul, Christelle
    Grabar, Sophie
    Spire, Bruno
    Meyer, Laurence
    Launay, Odile
    Aboulker, Jean-Pierre
    Bertone, Helene
    Brezin, Antoine
    Clot, Lionel
    Diallo, Alpha
    Dore, Veronique
    Fleury, Herve
    Krivine, Anne
    Lewden, Charlotte
    Lidove, Olivier
    Linard, Francoise
    Meiffredy, Vincent
    Moulignier, Antoine
    Pastor-Jean, Marie-Josephe
    Pollard, Helene
    Rieux, Veronique
    Ross, Anna-Laura
    De Sauniere, Anne
    Viard, Jean-Paul
    AIDS, 2019, 33 (13) : 2061 - 2071
  • [6] HIV Vaccine Trials Network (HVTN) 910: Long-term Follow-up of HIV Vaccine-induced Seropositivity (VISP) among HIV Vaccinees
    Hural, John
    Metch, Barbara
    Grunenberg, Nicole
    Allen, Mary
    Coombs, Robert
    Dragavon, Joan
    Puren, Adrian
    Singh, Beverly
    Maenza, Janine
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 2016, 32 : 101 - 101
  • [7] Vaccine-induced Seropositivity in Participants of the APPROACH Study (HIV-V-A004)
    Lavreys, L.
    Callewaert, K.
    Vingerhoets, J.
    Colfer, A.
    Pau, M. G.
    Tomaka, F.
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 2018, 34 : 185 - 185
  • [8] Exploring community understanding of HIV vaccine-induced seropositivity in Soshanguve, South Africa
    Malahleha, M.
    Malamatsho, R.
    Mbatsane, T. E.
    Keefer, M.
    Jean, J.
    JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, 2021, 24
  • [9] Evaluating the surrogacy of multiple vaccine-induced immune response biomarkers in HIV vaccine trials
    Dasgupta, Sayan
    Huang, Ying
    BIOSTATISTICS, 2021, 22 (02) : 421 - 436
  • [10] New HIV peptide-based immunoassay resolves vaccine-induced seropositivity in HIV vaccine (Phase III) trial participants
    O Penezina
    D Clapham
    J Collins
    V Kovalenko
    N Krueger
    IR Rodriguez-Chavez
    MP Busch
    AE Levin
    Retrovirology, 9
12345