Separation of nicotine metabolites by capillary zone electrophoresis and capillary zone electrophoresis/mass spectrometry

被引：0
|
作者：
Palmer, ME
Smith, RF
Chambers, K
Tetler, LW
机构：
[1] Sheffield Hallam Univ, Div Biomed Sci, Sheffield S1 1WB, S Yorkshire, England
[2] Sheffield Hallam Univ, Div Chem, Sheffield S1 1WB, S Yorkshire, England
[3] Sheffield Hallam Univ, Biomed Res Ctr, Sheffield S1 1WB, S Yorkshire, England
来源：
RAPID COMMUNICATIONS IN MASS SPECTROMETRY | 2001年 / 15卷 / 03期
关键词：
D O I：
10.1002/1097-0231(20010215)15:3<224::AID-RCM213>3.0.CO;2-Z
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
The use of capillary zone electrophoresis (CZE) and capillary zone electrophoresis/mass spectrometry (CZE/MS) has been demonstrated, in principle, for the separation of nicotine and nicotine metabolites. The buffer system developed for separation and detection by CZE/UV was modified for use in CZE/MS analysis. Several of the metabolites are isobaric and tandem mass spectrometric (MS/MS) techniques have been used to differentiate such analytes. Copyright (C) 2001 John Wiley & Sons, Ltd.
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收藏
页码：224 / 231
页数：8
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