Isolation of Sceletium alkaloids by high-speed countercurrent chromatography

被引：37
|
作者：
Shikanga, Emmanuel Amukohe [2 ]
Viljoen, Alvaro [3 ]
Combrinck, Sandra [2 ]
Marston, Andrew [1 ]
机构：
[1] Univ Free State, Dept Chem, ZA-9300 Bloemfontein, South Africa
[2] Tshwane Univ Technol, Dept Chem, ZA-0001 Pretoria, South Africa
[3] Tshwane Univ Technol, Dept Pharmaceut Sci, ZA-0001 Pretoria, South Africa
来源：
PHYTOCHEMISTRY LETTERS | 2011年 / 4卷 / 02期
基金：
新加坡国家研究基金会;
关键词：
Sceletium tortuosum; Mesembryanthemaceae; Mesembrine alkaloids; Isolation; High-speed countercurrent chromatography;
D O I：
10.1016/j.phytol.2011.03.003
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
The alkaloids of Sceletium tortuosum (Mesembryanthemaceae) exhibit important pharmacological properties and are used for the treatment of psychiatric and psychological conditions, including depression, anxiety, drug dependence, bulimia and obsessive-compulsive disorder. The all-liquid technique of high-speed countercurrent chromatography provides an excellent tool for the rapid isolation of these alkaloids in high yields. (C) 2011 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码：190 / 193
页数：4
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