A Single Transcription Factor Drives Toxoplasma gondii Differentiation

被引：1

作者：

Kochanowsky, Joshua A. ^{[1
]}

Koshy, Anita A. ^{[1
,2
,3
]}

机构：

[1] Univ Arizona, Dept Immunobiol, Tucson, AZ 85721 USA

[2] Univ Arizona, Dept Neurol, Tucson, AZ 85721 USA

[3] Univ Arizona, Bio5 Inst, Tucson, AZ 85721 USA

来源：

CELL | 2020年 / 180卷 / 02期

基金：

美国国家卫生研究院;

关键词：

SKELETAL-MUSCLE; CELLS;

D O I：

10.1016/j.cell.2019.12.038

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Microbes that cause persistent infections (e.g., herpes viruses) do so by switching from fast-growing lytic states to slow-growing latent states. Waldman et al. have identified a single transcription factor that governs the switch between the lytic and latent forms of Toxoplasma gondii, a parasite that causes a persistent brain infection.

引用

页码：216 / 218

页数：4

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