Aurantosides G, H, and I:: Three new tetramic acid glycosides from a Papua New Guinea Theonella swinhoei

被引：30

作者：

Ratnayake, AS

Davis, RA

Harper, MK

Veltri, CA

Andjelic, CD

Barrows, LR

Ireland, CM ^{[1
]}

机构：

[1] Univ Utah, Dept Med Chem, Salt Lake City, UT 84112 USA

[2] Univ Utah, Dept Pharmacol & Toxicol, Salt Lake City, UT 84112 USA

来源：

JOURNAL OF NATURAL PRODUCTS | 2005年 / 68卷 / 01期

关键词：

D O I：

10.1021/np049721s

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Aurantosides G-I (1-3) have been isolated from the lithistid sponge Theonella swinhoei from Papua New Guinea. Their structures were established by spectroscopic and chemical methods. Compounds 1-3 represent new monochloropentaenoyl tetramic acids with mono-, di-, and tri-N-saccharide substituents, respectively. Aurantosides G-I (1 -3) failed to show any significant cytotoxicity against the human colon tumor cell line HCT-116.

引用

页码：104 / 107

页数：4

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