Novel bridgehead nitrogen heterocyclic systems: Synthesis and antimicrobial activity of imidazo[1,2-d]-s-triazolo [3,4-b][1,3,4]thiadiazoles

被引：0

作者：

Mohan, J ^{[1
]}

Kataria, S ^{[1
]}

机构：

[1] Maharshi Dayanand Univ, Dept Chem, Rohtak 124001, Haryana, India

来源：

INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 1998年 / 37卷 / 07期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A facile synthesis of 7-aryl-3-ethylimidazo[1,2-d]-s-triazolo[3,4-b][1,3,4]thiadiazole 3 has been achieved by the condensation of 4-amino-3-ethyl-5-mercapto-s-triazole 1 with cyanogen bromide to yield 6-amino-3-ethyl-s-triazolo[3,4-b][1,3,4]thiadiazole 2 followed by treatment with alpha-haloketones. The structures 3 are supported by IR and H-1 NMR spectral data. The antibacterial and antifungal activities of the system have also been evaluated.

引用

页码：713 / 714

页数：2

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