Human Brain Structural Organization in Healthy Volunteers and Patients with Schizophrenia

被引:0
|
作者
Kartashov, Sergey [1 ,3 ]
Ushakov, Vadim [1 ,3 ]
Maslennikova, Alexandra [2 ]
Sboev, Alexander [1 ]
Selivanov, Anton [1 ]
Moloshnikov, Ivan [1 ]
Velichkovsky, Boris [1 ,4 ]
机构
[1] NRC Kurchatov Inst, Moscow, Russia
[2] RAS, Inst Higher Nervous Act & Neurophysiol, Moscow, Russia
[3] Natl Res Nucl Univ MEPhI, Moscow Engn Phys Inst, Moscow, Russia
[4] Tech Univ Dresden, Dresden, Germany
基金
俄罗斯科学基金会;
关键词
Diffusion; dMRI; Structural connections; Rich-club; Graph theory; RICH-CLUB ORGANIZATION;
D O I
10.1007/978-3-319-63940-6_12
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
The purpose of this work was to study and to compare the structural features of the human brain in two groups of people: healthy volunteers and patients with schizophrenia. According to the data of diffusion magnetic resonance imaging (dMRT), tractography pathways that describe the direction of fibers growth of the white matter of the human brain were reconstructed. Analysis of these paths made it possible to construct maps of the connectivity of all sections of the prepared brain to each other for each subject. With the help of graph theory, so-called rich-club areas were found for each of two groups, that, according to many papers, are the key centers of the brain in the transmission and exchange of information between all areas of the human brain.
引用
收藏
页码:85 / 90
页数:6
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