Goat's milk allergy

被引：22
|
作者：
Tavares, B. [2 ]
Pereira, C. [2 ]
Rodrigues, F. [1 ]
Loureiro, G. [2 ]
Chieira, C. [2 ]
机构：
[1] Coimbra Univ Hosp, Immunol Lab, Coimbra, Portugal
[2] Hosp Univ Coimbra, Serv Imunoalergol, P-3001301 Coimbra, Portugal
来源：
ALLERGOLOGIA ET IMMUNOPATHOLOGIA | 2007年 / 35卷 / 03期
关键词：
allergy; cheese; cow; goat; milk;
D O I：
10.1157/13106780
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
Background: Goat's milk (GM) allergy not associated with allergy to cow's milk (CM) is a rare disorder. Caseins have been implicated has the major allergens eliciting symptoms. Methods: We report the case of a 27 years-old female patient that experienced two episodes of urticaria related to ingestion of goat's cheese (GC). She tolerated CM, dairy products and sheep cheese. Skin prick tests were performed with GM, CM, bovine casein and a.-lactalbumin and fresh milk and GC. Serum specific IgE to GM, CM and its fractions, and GM and CM immunobloting assays with inhibition were also evaluated. Results: Skin tests were positive to GM and GC and negative to CM. GM immunoblot showed an IgE-binding 14 kDa band that was totally inhibited after serum pre-incubation with GM. Conclusions: Allergens other than casein can be involved in allergy to GM. Even small quantities of protein can elicit symptoms.
引用
收藏
页码：113 / 116
页数：4
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