Synthesis of stable carbohydrate mimetics as potential glycotherapeutics

被引：45
|
作者：
Postema, MHD [1 ]
Piper, JL [1 ]
Betts, RL [1 ]
机构：
[1] Henry Ford Hlth Syst, Dept Internal Med, Detroit, MI 48202 USA
来源：
SYNLETT | 2005年 / 09期
关键词：
carbohydrate mimetics; ring-closing metathesis; beta-C-glycosides;
D O I：
10.1055/s-2005-868500
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis of a variety of stable carbohydrate mimetics using a RCM approach is discussed. An esterification-RCM approach has been utilized for the preparation of a variety of alkyl, aryl beta-C-glycosides as well as a number of beta-C-saccharides.
引用
收藏
页码：1345 / 1358
页数：14
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