Serial intravascular ultrasound assessment of changes in coronary atherosclerotic plaque dimensions and composition: an update

被引：27
|
作者：
Hartmann, Marc [1 ]
Huisman, Jennifer [1 ]
Boese, Dirk [2 ]
Jensen, Lisette O. [3 ]
Schoenhagen, Paul [4 ,5 ]
Mintz, Gary S. [6 ]
Erbel, Raimund [2 ]
von Birgelen, Clemens [1 ,7 ]
机构：
[1] Thoraxcentrum Twente, Dept Cardiol, NL-7513 ER Enschede, Netherlands
[2] Univ Duisburg Essen, Dept Cardiol, Essen, Germany
[3] Odense Univ Hosp, Dept Cardiol, DK-5000 Odense C, Denmark
[4] Cleveland Clin Fdn, Dept Cardiol, Cleveland, OH 44195 USA
[5] Cleveland Clin Fdn, Div Radiol, Cleveland, OH 44195 USA
[6] Cardiovasc Res Fdn, New York, NY USA
[7] Univ Twente, MIRA Inst, NL-7500 AE Enschede, Netherlands
来源：
EUROPEAN JOURNAL OF ECHOCARDIOGRAPHY | 2011年 / 12卷 / 04期
关键词：
Coronary disease; Intravascular ultrasound; Radiofrequency; Serial studies; Progression-regression; Plaque vulnerability; RANDOMIZED CONTROLLED-TRIAL; LIPID-LOWERING THERAPY; TERM GREATER-THAN-OR-EQUAL-TO-12 MONTHS; RADIOFREQUENCY DATA-ANALYSIS; MONTHS FOLLOW-UP; OPTICAL COHERENCE TOMOGRAPHY; THIN-CAP FIBROATHEROMA; ARTERY-DISEASE; IN-VIVO; VIRTUAL HISTOLOGY;
D O I：
10.1093/ejechocard/jer017
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
This manuscript reviews the use of serial intravascular ultrasound (IVUS) examination of coronary atherosclerosis in recent observational studies and randomized trials that revealed the effects of cholesterol-lowering and lipid-modifying therapies and offered novel insight into plaque progression and regression. We discuss the value of plaque progression-regression as complementary imaging endpoint and potential surrogate marker of cardiovascular event risk. In addition, the progress in serial assessment of coronary plaque composition and plaque vulnerability by radiofrequency-based analyses is reviewed. Finally, we report on the evaluation of true vessel remodelling in recent serial IVUS trials and discuss the future perspective of serial invasive imaging of coronary atherosclerosis.
引用
收藏
页码：313 / 321
页数：9
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