A Drug Screen Based on Protein-Fragment Complementation Identifies Drugs That Reduce Early Oligomer Formation by the SCA3 Polyglutamine Disease Protein

被引：0
|
作者：
Tada, Masayoshi
McQuade, Thomas
Kerppola, Tom
Decker, Stuart
Paulson, Henry
机构：
来源：
NEUROLOGY | 2011年 / 76卷 / 09期
关键词：
D O I：
暂无
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
引用
收藏
页码：A346 / A346
页数：1
相关论文
共 5 条
  • [1] Universal strategies in research and drug discovery based on protein-fragment complementation assays
    Stephen W. Michnick
    Po Hien Ear
    Emily N. Manderson
    Ingrid Remy
    Eduard Stefan
    Nature Reviews Drug Discovery, 2007, 6 : 569 - 582
  • [2] Universal strategies in research and drug discovery based on protein-fragment complementation assays
    Michnick, Stephen W.
    Ear, Po Hien
    Manderson, Emily N.
    Remy, Ingrid
    Stefan, Eduard
    NATURE REVIEWS DRUG DISCOVERY, 2007, 6 (07) : 569 - 582
  • [3] Unbiased screen identifies aripiprazole as a modulator of abundance of the polyglutamine disease protein, ataxin-3
    Costa, Maria do Carmo
    Ashraf, Naila S.
    Fischer, Svetlana
    Yang, Yemen
    Schapka, Emily
    Joshi, Gnanada
    McQuade, Thomas J.
    Dharia, Rahil M.
    Dulchavsky, Mark
    Ouyang, Michelle
    Cook, David
    Sun, Duxin
    Larsen, Martha J.
    Gestwicki, Jason E.
    Todi, Sokol V.
    Ivanova, Magdalena I.
    Paulson, Henry L.
    BRAIN, 2016, 139 : 2891 - 2908
  • [4] Ubiquitinated nuclear inclusions of expanded polyglutamine protein in spinocerebellar ataxia type 3/Machado-Joseph disease (SCA3/MJD)
    Paulson, HL
    Vig, PJS
    Subramony, SH
    Fratkin, JD
    NEUROLOGY, 1998, 50 (04) : A310 - A310
  • [5] A novel retrovirus-based protein-fragment complementation assay screen in mammalian cells reveals known and novel interaction partners for AKT1
    Ding, Zhiyong
    Liang, Jiyong
    Lu, Yiling
    Lin, Shiaw-Yih
    Mills, Gordon B.
    CANCER RESEARCH, 2006, 66 (08)
1