Structure and functions of tumor necrosis factor-α converting enzyme

被引：0
|
作者：
Mezyk, R [1 ]
Bzowska, M [1 ]
Bereta, J [1 ]
机构：
[1] Jagiellonian Univ, Fac Biotechnol, Dept Cell Biochem, PL-30387 Krakow, Poland
来源：
ACTA BIOCHIMICA POLONICA | 2003年 / 50卷 / 03期
关键词：
TACE; secretase; shedding; TNF alpha; ADAM family;
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Tumor necrosis factor-alpha converting enzyme (TACE) is the first described and best characterized secretase. In this review the structure and the possible roles for TACE are summarized. The substrate specificity and the regulation of TACE activity as well as redundancy and possible cooperations of distinct secretases are also discussed.
引用
收藏
页码：625 / 645
页数：21
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