Recurrent malignant solitary fibrous tumor of the scalp a case report and literature review

被引:4
|
作者
Rabie, Ahmed [1 ]
Hasan, Abdulkarim [2 ]
Mohammed, Yasein [2 ]
Abdelmaksoud, Ayman [3 ]
Rabaan, Ali A. [4 ]
机构
[1] Al Azhar Univ, Damietta Branch, Dept Pathol, Fac Med, Dumyat, Egypt
[2] Al Azhar Univ, Dept Pathol, Fac Med, Cairo 11884, Egypt
[3] Venereol & Leprosy Hosp, Mansoura Dermatol, Mansoura, Egypt
[4] Johns Hopkins Aramco Healthcare Dhahran, Mol Diagnost Lab, Dhahran, Saudi Arabia
关键词
Solitary fibrous tumor; Skin cancer; Immunohistochemistry; STAT6; SKIN;
D O I
10.4132/jptm.2021.10.29
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Solitary fibrous tumor (SFT) is a rare type of mesenchymal neoplasm that first was discovered in the pleura but can also affect the peritoneum, lungs, mediastinum, and skin. Cutaneous malignant SFT is an extremely rare tumor that resembles dermatofibrosacoma protuberance (DFSP) histologically and immunohistochemically. Herein, we describe a case of malignant SFT that presented as a recurrent mass on the scalp. The first lesion was totally excised one year before recurrence and was diagnosed as a DFSP based on the histopathology and cluster of differentiation 34 immunostaining positivity. Re-examination of the previously examined specimen was considered. Activator of transcription 6 positivity was also detected in the tissue, confirming the diagnosis of a recurrent malignant SFT rather than DFSP. There was no evidence of recurrence, locoregional, or distant metastases at six months after lesion removal with a safety margin.
引用
收藏
页码:103 / 108
页数:6
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