Survival Analysis of Pathological T3a Upstaging in Clinical T1 Renal Cell Carcinoma

被引：5
|
作者：
Lai, Gu-Shun [1 ]
Li, Jian-Ri [2 ,3 ,4 ]
Wang, Shian-Shiang [2 ,3 ,5 ]
Chen, Chuan-Shu [2 ,3 ]
Yang, Chun-Kuang [2 ]
Hung, Sheng-Chun [2 ,3 ]
Cheng, Chen-Li [2 ,3 ]
Ou, Yen-Chuan [3 ,6 ]
Chiu, Kun-Yuan [2 ,5 ]
机构：
[1] Taichung Vet Gen Hosp, Chiayi Branch, Dept Surg, Div Urol, Chiayi, Taiwan
[2] Taichung Vet Gen Hosp, Dept Surg, Div Urol, Taichung, Taiwan
[3] Chung Shan Med Univ, Inst Med, Taichung, Taiwan
[4] Hungkuang Univ, Dept Med & Nursing, Taichung, Taiwan
[5] Natl Chi Nan Univ, Dept Appl Chem, Nantou, Taiwan
[6] Tungs Taichung MetroHarbor Hosp, Dept Urol, Taichung, Taiwan
来源：
IN VIVO | 2020年 / 34卷 / 02期
关键词：
Pathological T3a upstaging; renal cell carcinoma; survival; POSITIVE SURGICAL MARGINS; PARTIAL NEPHRECTOMY; RECURRENCE; MASSES; GUIDELINES; PREDICTORS; SURGERY; IMPACT;
D O I：
10.21873/invivo.11841
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Aim: To evaluate the oncological outcomes of pathological T3a upstaging from clinical T1 renal cell carcinoma. Patients and Methods: We retrospectively studied patients who underwent radical or partial nephrectomy for clinical T1 renal tumors. Results: The median follow-up period was 44 months. At three and five years, the respective overall survival rate was 88.7% and 82.4% in pT3a disease, 95.7% and 93.4% in pT1 (p=0.008), the cancer-specific survival rate, 93.9% and 90.8% in pT3a, 99% and 97.7% in pT1 (p=0.001), and the recurrence-free survival rate, 79.7% and 71.0% in pT3a, and 95.5 and 94.3% in pT1 (p<0.001). Conclusion: Patients with pathological T3a upstaging tumors were associated with a significantly decreased survival rate, along with a higher recurrence rate when compared to those with pathological T1 disease.
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页码：799 / 805
页数：7
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