Brushing off antigenicity

被引：10
|
作者：
Lee, Kang Choon [1 ]
Lee, Seulki [2 ,3 ]
机构：
[1] Sungkyunkwan Univ, Sch Pharm, Suwon 16469, South Korea
[2] Johns Hopkins Univ, Sch Med, Wilmer Eye Inst, Russell H Morgan Dept Radiol & Radiol Sci, Baltimore, MD 21287 USA
[3] Johns Hopkins Univ, Sch Med, Wilmer Eye Inst, Ctr Nanomed, Baltimore, MD 21287 USA
来源：
NATURE BIOMEDICAL ENGINEERING | 2017年 / 1卷 / 01期
关键词：
PEG;
D O I：
10.1038/s41551-016-0019
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
Conjugation of a diabetes drug with a brush polymer reduces the reactivity of the drug conjugate towards pre-existing polymer antibodies in human plasma and improves the drug's performance in diabetic mice.
引用
收藏
页数：2
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