Raman imaging of drug delivery systems

被引：98
|
作者：
Smith, Geoffrey P. S. [1 ]
McGoverin, Cushla M. [2 ]
Fraser, Sara J. [1 ]
Gordon, Keith C. [1 ]
机构：
[1] Univ Otago, Dept Chem, Dodd Walls Ctr Photon & Quantum Technol, MacDiarmid Inst Adv Mat & Nanotechnol, Dunedin, New Zealand
[2] Univ Auckland, Dept Phys, Dodd Walls Ctr Photon & Quantum Technol, Auckland 1, New Zealand
来源：
ADVANCED DRUG DELIVERY REVIEWS | 2015年 / 89卷
关键词：
Raman imaging; Drug delivery; Chemometrics; Multivariate methods; Pre-processing; Solid dispersions; Drug dissolution; Polymeric microparticles; TARGET ENTROPY MINIMIZATION; SOLID DISPERSIONS; HUMAN SKIN; PACLITAXEL DISTRIBUTION; DEPTH RESOLUTION; STRATUM-CORNEUM; IR SPECTROSCOPY; MOLECULAR-LEVEL; DOSAGE FORMS; MICROSCOPY;
D O I：
10.1016/j.addr.2015.01.005
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
This review article includes an introduction to the principals of Raman spectroscopy, an outline of the experimental systems used for Raman imaging and the associated important considerations and limitations of this method. Common spectral analysis methods are briefly described and examples of interesting published studies which utilised Raman imaging of pharmaceutical and biomedical devices are discussed, along with summary tables of the literature at this point in time. (C) 2015 Elsevier B.V. All rights reserved.
引用
收藏
页码：21 / 41
页数：21
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