Catalytic Functionalization of C-H Bonds of Azulene by Carbene/Nitrene Incorporation

被引：17

作者：

Carreras, Javier ^{[1
,2
]}

Popowski, Yanay ^{[3
]}

Caballero, Ana ^{[1
,2
]}

Amir, Elizabeth ^{[3
]}

Perez, Pedro J. ^{[1
,2
]}

机构：

[1] Univ Huelva, CIQSO Ctr Invest Quim Sostenible, Lab Catalisis Homogenea, CSIC,Unidad Asociada, Huelva 21007, Spain

[2] Univ Huelva, Dept Quim, Huelva 21007, Spain

[3] Shenkar Coll, Dept Polymers & Plast Engn, IL-52526 Ramat Gan, Israel

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2018年 / 83卷 / 18期

关键词：

CARBON-HYDROGEN BONDS; ELECTRON-RICH ARENES; METHYL VINYL KETONE; CARBENE INSERTION; ETHYL DIAZOACETATE; COPPER(I)-HOMOSCORPIONATE CATALYSTS; PROPARGYLIC ALCOHOLS; AROMATIC-COMPOUNDS; ACTIVATION; COMPLEXES;

D O I：

10.1021/acs.joc.8b01731

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The selective catalytic functionalization of the C-H bond of azulene upon incorporation of carbene or nitrene units with metal-based catalysts is described. Ethyl diazoacetate or ArI=NTs are employed as carbene or nitrene precursors, respectively. The azulene derivatives are subsequently employed as building blocks toward more complex structures with potential use as biodegradable materials.

引用

页码：11125 / 11132

页数：8

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