Oral Artesunate-Amodiaquine and Artemether-Lumefantrine in the Treatment of Uncomplicated Hyperparasitaemic Plasmodium falciparum Malaria in Children

被引：5
|
作者：
Gbotosho, Grace O.
Sowunmi, Akintunde
Okuboyejo, Titilope M.
Happi, Christian T.
机构：
[1] Univ Ibadan, Dept Pharmacol & Therapeut, Ibadan, Nigeria
[2] Univ Ibadan, Inst Med Res & Training, Ibadan, Nigeria
来源：
JOURNAL OF TROPICAL PEDIATRICS | 2012年 / 58卷 / 02期
关键词：
artemisinin-based combinations; hyperparasitaemia; efficacy;
D O I：
10.1093/tropej/fmr045
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
The therapeutic efficacy, changes in haematocrit and declines in parasitaemias were evaluated in 56 children with uncomplicated falciparum hyperparasitaemia after oral artesunate-amodiaquine or artemether-lumefantrine. All children recovered clinically within 2 days and without progression to severe malaria. Falls in haematocrit in the first 3 days after treatment began were similar and < 5%. Declines in parasitaemias were monoexponential with both treatments with an estimated half-life of 1 h.
引用
收藏
页码：151 / 153
页数：3
相关论文
共 50 条
  • [1] EFFICACY OF ARTESUNATE-AMODIAQUINE AND ARTEMETHER-LUMEFANTRINE FOR UNCOMPLICATED PLASMODIUM FALCIPARUM MALARIA IN MADAGASCAR
    Rakotondrandriana, Antsa
    Rakotoarisoa, Arinomenjanahary
    Rakotomanga, Tovonahary Angelo
    Rason, Marie Ange
    Dentinger, Catherine M.
    Steinhardt, Laura Claire
    Souza, Samaly
    Lucchi, Naomi
    Udhayakumar, Venkatachalam
    Halsey, Eric
    Ratsimbasoa, Arsene
    [J]. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2019, 101 : 82 - 83
  • [2] Efficacy of artemether-lumefantrine and artesunate-amodiaquine for treating uncomplicated falciparum malaria in children
    Faranita, Tri
    Pasaribu, Ayodhia Pitaloka
    Ali, Muhammad
    Lubis, Munar
    Pasaribu, Syahril
    [J]. PAEDIATRICA INDONESIANA, 2012, 52 (05) : 260 - 266
  • [3] Efficacy of artesunate-amodiaquine and artemether-lumefantrine for uncomplicated Plasmodium falciparum malaria in Madagascar, 2018
    Dentinger, Catherine M.
    Rakotomanga, Tovonahary Angelo
    Rakotondrandriana, Antsa
    Rakotoarisoa, Arinomenjanahary
    Rason, Marie Ange
    Moriarty, Leah F.
    Steinhardt, Laura C.
    Kapesa, Laurent
    Razafindrakoto, Jocelyn
    Svigel, Samaly S.
    Lucchi, Naomi W.
    Udhayakumar, Venkatachalam
    Halsey, Eric S.
    Ratsimbasoa, C. Arsene
    [J]. MALARIA JOURNAL, 2021, 20 (01)
  • [4] Efficacy of artesunate-amodiaquine and artemether-lumefantrine for uncomplicated Plasmodium falciparum malaria in Madagascar, 2018
    Catherine M. Dentinger
    Tovonahary Angelo Rakotomanga
    Antsa Rakotondrandriana
    Arinomenjanahary Rakotoarisoa
    Marie Ange Rason
    Leah F. Moriarty
    Laura C. Steinhardt
    Laurent Kapesa
    Jocelyn Razafindrakoto
    Samaly S. Svigel
    Naomi W. Lucchi
    Venkatachalam Udhayakumar
    Eric S. Halsey
    C. Arsène Ratsimbasoa
    [J]. Malaria Journal, 20
  • [5] Efficacy of artemether-lumefantrine and artesunate-amodiaquine for the treatment of uncomplicated falciparum malaria in Tanzania
    Kabanywanyi, A. M.
    Ishengoma, D. S.
    Namamba, J.
    Ngasala, B.
    Njau, R.
    Kataraihya, J.
    Lemnge, M. M.
    Premji, Z.
    [J]. TROPICAL MEDICINE & INTERNATIONAL HEALTH, 2011, 16 : 102 - 103
  • [6] In vivo efficacy of artemether-lumefantrine and artesunate-amodiaquine for uncomplicated Plasmodium falciparum malaria in Malawi, 2014
    Magdalena Paczkowski
    Dyson Mwandama
    Daniel Marthey
    Madalitso Luka
    Georgina Makuta
    John Sande
    Doreen Ali
    Peter Troell
    Don P. Mathanga
    Julie Gutman
    [J]. Malaria Journal, 15
  • [7] In vivo efficacy of artemether-lumefantrine and artesunate-amodiaquine for uncomplicated Plasmodium falciparum malaria in Malawi, 2014
    Paczkowski, Magdalena
    Mwandama, Dyson
    Marthey, Daniel
    Luka, Madalitso
    Makuta, Georgina
    Sande, John
    Ali, Doreen
    Troell, Peter
    Mathanga, Don P.
    Gutman, Julie
    [J]. MALARIA JOURNAL, 2016, 15
  • [8] EFFICACY OF ARTEMETHER-LUMEFANTRINE OR ARTESUNATE-AMODIAQUINE FOR UNCOMPLICATED PLASMODIUM FALCIPARUM MALARIA-MALAWI, 2014
    Paczkowski, Magdalena
    Mwandama, Dyson
    Marthey, Daniel
    Luka, Madalitso
    Makuta, Georgina
    Sande, John
    Ali, Doreen
    Troell, Peter
    Mathanga, Don
    Gutman, Julie
    [J]. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2015, 93 (04): : 108 - 108
  • [9] Efficacy and safety of artemether-lumefantrine and artesunate-amodiaquine in treating children with uncomplicated Plasmodium falciparum malaria in mainland Tanzania
    Syk, A.
    Mork, L. G.
    Mmbando, B.
    Mhamilawa, L. E.
    Ngasala, B.
    Martensson, A.
    [J]. TROPICAL MEDICINE & INTERNATIONAL HEALTH, 2021, 26 : 97 - 97
  • [10] Comparative effect of artemether-lumefantrine and artesunate-amodiaquine on gametocyte clearance in children with uncomplicated Plasmodium falciparum malaria in Madagascar
    Rakotoarisoa, Malalanandrianina A.
    Fenomanana, Jocia
    Dodoson, Bronislaw Tchesterico
    Andrianaranjaka, Voahangy Hanitriniaina I.
    Ratsimbasoa, Arsene
    [J]. MALARIA JOURNAL, 2022, 21 (01)
12345