QUALITY-OF-LIFE;
DEEP BRAIN-STIMULATION;
TRANSCRANIAL MAGNETIC STIMULATION;
NONMOTOR SYMPTOMS;
NEUROPSYCHIATRIC SYMPTOMS;
DOUBLE-BLIND;
BEHAVIORAL-DISORDERS;
CEREBROSPINAL-FLUID;
SLEEP DISORDERS;
RATING-SCALES;
D O I:
10.1016/bs.im.2017.05.024
中图分类号:
R74 [神经病学与精神病学];
学科分类号:
摘要:
Depression and anxiety are some of the most common comorbidities arising in patients with Parkinson's disease. However, their timely recognition and diagnosis are often hindered by overlap with other somatic features and a low rate of self-report. There is a need for greater awareness and for better assessment and treatment options are highly required. Currently available scales can serve as tools to monitor change over time and the effect of interventional strategies. Development of new therapeutic strategies, including nonpharmacological approaches such as transcranial magnetic stimulation and deep brain stimulation, may provide alternatives to currently available treatment approaches. In this chapter we will give an overview of the most recent advances in the diagnosis and treatment of these important nonmotor symptoms.
机构:
Univ London, Dept Mol Neurosci, London WC1N 1PJ, England
Univ London, Reta Lila Weston Inst Neurol Studies, London WC1N 1PJ, EnglandUniv London, Dept Mol Neurosci, London WC1N 1PJ, England
Djamshidian, Atbin
Friedman, Joseph H.
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机构:
Brown Univ, Butler Hosp, Movement Disorders Program, Providence, RI 02912 USA
Brown Univ, Alpert Med Sch, Dept Neurol, Providence, RI 02912 USAUniv London, Dept Mol Neurosci, London WC1N 1PJ, England
机构:
Kuvatov Republican Clinical Hospital, Ufa
Medstantart Republican Consultative-Diagnostic Center for Extrapyramidal Pathology and Botulinotherapy, Ufa
Institute of Biochemistry and Genetics, Ufa Scientific Center, UfaKuvatov Republican Clinical Hospital, Ufa
Akhmadeeva G.N.
Magzhanov R.V.
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机构:
Department of Neurology with Neurosurgery and Medical Genetics, Bashkir State Medical University, Russian Ministry of Health, UfaKuvatov Republican Clinical Hospital, Ufa
Magzhanov R.V.
Tayupova G.N.
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机构:
Kuvatov Republican Clinical Hospital, Ufa
Medstantart Republican Consultative-Diagnostic Center for Extrapyramidal Pathology and Botulinotherapy, UfaKuvatov Republican Clinical Hospital, Ufa
Tayupova G.N.
Baitimerov A.R.
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机构:
Medstantart Republican Consultative-Diagnostic Center for Extrapyramidal Pathology and Botulinotherapy, UfaKuvatov Republican Clinical Hospital, Ufa
Baitimerov A.R.
Khidiyatova I.M.
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机构:
Institute of Biochemistry and Genetics, Ufa Scientific Center, UfaKuvatov Republican Clinical Hospital, Ufa
机构:
Toho Univ, Omori Med Ctr, Dept Neurol, Ota Ku, Tokyo 1438541, Japan
Methodist Neurol Inst, Dept Neurol, Houston, TX 77030 USAToho Univ, Omori Med Ctr, Dept Neurol, Ota Ku, Tokyo 1438541, Japan
Kano, Osamu
Ikeda, Ken
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机构:
Toho Univ, Omori Med Ctr, Dept Neurol, Ota Ku, Tokyo 1438541, JapanToho Univ, Omori Med Ctr, Dept Neurol, Ota Ku, Tokyo 1438541, Japan
Ikeda, Ken
Cridebring, Derek
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机构:
Methodist Hosp, Res Inst, Dept Bioinformat & Bioengn, Houston, TX 77030 USAToho Univ, Omori Med Ctr, Dept Neurol, Ota Ku, Tokyo 1438541, Japan
Cridebring, Derek
Takazawa, Takanori
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机构:
Toho Univ, Omori Med Ctr, Dept Neurol, Ota Ku, Tokyo 1438541, JapanToho Univ, Omori Med Ctr, Dept Neurol, Ota Ku, Tokyo 1438541, Japan
Takazawa, Takanori
Yoshii, Yasuhiro
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机构:
Toho Univ, Omori Med Ctr, Dept Neurol, Ota Ku, Tokyo 1438541, JapanToho Univ, Omori Med Ctr, Dept Neurol, Ota Ku, Tokyo 1438541, Japan
Yoshii, Yasuhiro
Iwasaki, Yasuo
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机构:
Toho Univ, Omori Med Ctr, Dept Neurol, Ota Ku, Tokyo 1438541, JapanToho Univ, Omori Med Ctr, Dept Neurol, Ota Ku, Tokyo 1438541, Japan
机构:
Carlos III Inst Hlth, Area Appl Epidemiol, Natl Ctr Epidemiol, Madrid 28029, SpainCarlos III Inst Hlth, Area Appl Epidemiol, Natl Ctr Epidemiol, Madrid 28029, Spain
Martinez-Martin, Pablo
Damian, Javier
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机构:
Carlos III Inst Hlth, Area Appl Epidemiol, Natl Ctr Epidemiol, Madrid 28029, SpainCarlos III Inst Hlth, Area Appl Epidemiol, Natl Ctr Epidemiol, Madrid 28029, Spain