D-dimer in patients infected with COVID-19 and suspected pulmonary embolism

被引：56
|
作者：
Garcia-Olive, Ignasi [1 ,2 ,3 ]
Sintes, Helena [1 ,4 ]
Radua, Joaquim [5 ,6 ,7 ,8 ]
Abad Capa, Jorge [1 ,2 ,3 ,4 ]
Rosell, Antoni [1 ,2 ,3 ,4 ]
机构：
[1] Hosp Badalona Germans Trias & Pujol, Serv Pneumol, Carretera Canyet Sn, Barcelona 08916, Spain
[2] Ciber Enfermedades Resp, CibeRes, Bunyola, Spain
[3] Germans Trias & Pujol Res Inst IGTP, Barcelona, Spain
[4] Univ Autonoma Barcelona, Dept Med, Barcelona, Spain
[5] Inst Invest Biomed August Pi i Sunyer IDIBAPS, Imaging Mood & Anxiety Related Disorders IMARD Gr, Barcelona, Spain
[6] CIBERSAM, Madrid, Spain
[7] Kings Coll London, Inst Psychiat Psychol & Neurosci, Early Psychosis Intervent & Clin Detect EPIC Lab, London, England
[8] Karolinska Inst, Stockholm Cty Council, Dept Clin Neurosci, Stockholm Hlth Care Serv, Stockholm, Sweden
来源：
RESPIRATORY MEDICINE | 2020年 / 169卷
关键词：
COVID-19; D-dimer; Pulmonary embolism;
D O I：
10.1016/j.rmed.2020.106023
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Objective: To analyze the risk factors for pulmonary embolism (PE) in patients infected with COVID-19. Methods: We conducted an observational, retrospective study. Patients with severe infection with COVID-19 and suspected PE were included. Results: Patients with higher levels of D-dimer and those requiring intubation were at a higher risk of developing PE. Higher D-dimer levels were associated with a greater probability of PE 3, 6, 9 and 12 days after determining D-dimer levels with an OR of 1.7, 2.0, 2.4 and 2.4, respectively. Conclusion: In conclusion, patients infected with COVID-19 requiring OTI with higher levels of D-dimer have an increased risk of developing PE.
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页数：3
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