Senescence marker protein-30 (SMP30) and its gerontological significance

被引：0
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作者：
Fujita, T
Shirasawa, T
Maruyama, N
机构：
[1] Tokyo Metropolitan Inst Gerontol, Dept Mol Pathol, Itabashi Ku, Tokyo 173, Japan
[2] Tokyo Metropolitan Inst Gerontol, Dept Neurophysiol, Itabashi Ku, Tokyo 173, Japan
来源：
CURRENT SCIENCE | 1998年 / 74卷 / 10期
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D O I：
暂无
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
We have isolated and characterized a novel protein designated as senescence marker protein-30 (SMP30). The amount of SMP30 decreases in an androgen-independent manner with increasing age in the rat liver. SMP30 turned out to be identical to a calcium-binding protein called regucalcin. In this review; we give an overview of the structure, expression and possible physiological role(s) of SMP30. We also discuss the hypothetical role of SMP30 in aging and calcium homeostasis.
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页码：872 / 877
页数：6
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