Safety of repeated doses of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine in adults and adolescents

被引：6

作者：

Jackson, Michael L. ^{[1
]}

Yu, Onchee ^{[1
]}

Nelson, Jennifer C. ^{[1
]}

Nordin, James D. ^{[2
]}

Tartof, Sara Y. ^{[3
]}

Klein, Nicola P. ^{[4
]}

Donahue, James G. ^{[5
]}

Irving, Stephanie A. ^{[6
]}

Glanz, Jason M. ^{[7
]}

McNeil, Michael M. ^{[8
]}

Jackson, Lisa A. ^{[1
]}

机构：

[1] Kaiser Permanente Washington Hlth Res Inst, Seattle, WA 98101 USA

[2] Hlth Partners Inst, Minneapolis, MN USA

[3] Kaiser Permanente Southern Calif, Pasadena, CA USA

[4] Kaiser Permanente Northern Calif, Oakland, CA USA

[5] Marshfield Clin Res Inst, Marshfield, WI USA

[6] Kaiser Permanente Northwest, Portland, OR USA

[7] Kaiser Permanente Colorado, Denver, CO USA

[8] Ctr Dis Control & Prevent, Atlanta, GA USA

来源：

PHARMACOEPIDEMIOLOGY AND DRUG SAFETY | 2018年 / 27卷 / 08期

关键词：

pharmacoepidemiology; vaccination; whooping cough; IMMUNIZATION PRACTICES ACIP; ANTIGEN CONTENT DIPHTHERIA; ADVISORY-COMMITTEE; PREGNANT-WOMEN; TDAP VACCINE; RECOMMENDATIONS; SURVEILLANCE; DATALINK; EVENTS;

D O I：

10.1002/pds.4569

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

In light of waning immunity to pertussis following receipt of tetanus toxoid, reduced diphtheria toxoid and acellular pertussis (Tdap) vaccine, maintaining protection may require repeated Tdap vaccination. We evaluated the safety of repeated doses of tetanus-containing vaccine in 68915 nonpregnant adolescents and adults in the Vaccine Safety Datalink population who had received an initial dose of Tdap. Compared with 7521 subjects who received a subsequent dose of tetanus toxoid, reduced diphtheria (Td) vaccine, the 61394 subjects who received a subsequent dose of Tdap did not have significantly elevated risk of medical visits for seizure, cranial nerve disorders, limb swelling, pain in limb, cellulitis, paralytic syndromes, or encephalopathy/encephalitis/meningitis. These results suggest that repeated Tdap vaccination has acceptable safety relative to Tdap vaccination followed by Td vaccination.

引用

页码：921 / 925

页数：5

共 50 条

[1] Prevention of pertussis among adolescents: Recommendations for use of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine
Powell, KR
Baltimore, RS
Bernstein, HH
Bocchini, JA
Bradley, JS
Brady, MT
Dennehy, PH
Frenck, RW
Kimberlin, DW
Long, SS
McMillan, JA
Rubin, LG
[J]. PEDIATRICS, 2006, 117 (03) : 965 - 978
[2] Safety and immunogenicity of a tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine when co-administered with influenza vaccine in adults
Weston, Wayde M.
Chandrashekar, Vijayalakshmi
Friedland, Leonard R.
Howe, Barbara
[J]. HUMAN VACCINES, 2009, 5 (12): : 858 - 866
[3] Vaccine effectiveness of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine during a pertussis outbreak in Maine
Terranella, Andrew
Rea, Vicki
Griffith, Matthew
Manning, Susan
Sears, Steven
Farmer, Ann
Martin, Stacey
Patel, Manisha
[J]. VACCINE, 2016, 34 (22) : 2496 - 2500
[4] Safety of Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis and Influenza Vaccinations in Pregnancy
Sukumaran, Lakshmi
McCarthy, Natalie L.
Kharbanda, Elyse O.
Weintraub, Eric S.
Vazquez-Benitez, Gabriela
McNeil, Michael M.
Li, Rongxia
Klein, Nicola P.
Hambidge, Simon J.
Naleway, Allison L.
Lugg, Marlene M.
Jackson, Michael L.
King, Jennifer P.
DeStefano, Frank
Omer, Saad B.
Orenstein, Walter A.
[J]. OBSTETRICS AND GYNECOLOGY, 2015, 126 (05): : 1069 - 1074
[5] Safety and immunogenicity of an indigenously developed tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine (Tdap) in adults, adolescents, and children in India
Sharma, Hitt J.
Parekh, Sameer
Pujari, Pramod
Shewale, Sunil
Desai, Shivani
Kawade, Anand
Ravi, Mandyam
Oswal, Jitendra
James, Saji
Mahantashetti, N.
Munshi, Renuka
Ghosh, Apurba
Rao, Venkateshwar
Balsubramaniam, Sundaram
Varughese, P.
Somshekhar, A.
Ginsburg, Amy Sarah
Rao, Harish
Gautam, Manish
Gairola, Sunil
Shaligram, Umesh
[J]. EXPERT REVIEW OF VACCINES, 2023, 22 (01) : 278 - 287
[6] Reactogenicity of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine (Tdap) in pregnant women
Fortner, Kimberly B.
Edwards, Kathryn M.
Broder, Karen R.
Jimenez, Natalia
Zhu, Yuwei
Walter, Emmanuel B.
Heine, Robert P.
Moro, Pedro
Liang, Jennifer L.
Swamy, Geeta K.
[J]. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2016, 214 (01) : S193 - S194
[7] Reactogenicity and immunogenicity of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine (Tdap) in pregnant and nonpregnant women
Fortner, Kimberly B.
Swamy, Geeta K.
Broder, Karen R.
Jimenez-Truque, Natalia
Zhu, Yuwei
Moro, Pedro L.
Liang, Jennifer
Walter, Emmanuel B.
Heine, R. Phillips
Moody, M. Anthony
Yoder, Sandra
Edwards, Kathryn M.
[J]. VACCINE, 2018, 36 (42) : 6354 - 6360
[8] Immunogenicity and safety of a tetanus toxoid, reduced diphtheria toxoid and three-component acellular pertussis vaccine in adults 19-64 years of age
Blatter, Mark
Friedland, Leonard R.
Weston, Wayde M.
Li, Ping
Howe, Barbara
[J]. VACCINE, 2009, 27 (05) : 765 - 772
[9] Immune responses in adults to revaccination with a tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine 10 years after a previous dose
Halperin, Scott A.
Scheifele, David
De Serres, Gaston
Noya, Francisco
Meekison, William
Zickler, Paul
Larrivee, Luc
Langley, Joanne M.
McNeil, Shelly A.
Dobson, Simon
Jordanov, Emilia
Thakur, Manoj
Decker, Michael D.
Johnson, David R.
[J]. VACCINE, 2012, 30 (05) : 974 - 982
[10] Guillain-Barré syndrome after tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine: A case report
Ammar H.
[J]. Journal of Medical Case Reports, 5 (1)

← 1 2 3 4 5 →