Scanning force microscopy in the applied biological sciences

被引：26

作者：

Reich, Z ^{[1
]}

Kapon, R ^{[1
]}

Nevo, R ^{[1
]}

Pilpel, Y ^{[1
]}

Zmora, S ^{[1
]}

Scolnik, Y ^{[1
]}

机构：

[1] Weizmann Inst Sci, Dept Biol Chem, IL-76100 Rehovot, Israel

来源：

BIOTECHNOLOGY ADVANCES | 2001年 / 19卷 / 06期

基金：

以色列科学基金会;

关键词：

scanning probe microscopy; force spectroscopy; biotechnology;

D O I：

10.1016/S0734-9750(01)00077-5

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Fifteen years after its invention, the scanning force microscope (SFM) is rooted deep in the biological sciences. Here we discuss the use of SFM in biotechnology and biomedical research. The spectrum of applications reviewed includes imaging, force spectroscopy and mapping, as well as sensor applications. It is our hope that this review will be useful for researchers considering the use of SFM in their studies but are uncertain about its scope of capabilities. For the benefit of readers unfamiliar with SFM technology, the fundamentals of SFM imaging and force measurement are also briefly introduced. (C) 2001 Elsevier Science Inc. All rights reserved.

引用

页码：451 / 485

页数：35

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