Rapid Detection and Characterization of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Omicron Variant in a Returning Traveler

被引:5
|
作者
Sexton, Mary Elizabeth [1 ]
Waggoner, Jesse J. [1 ]
Carmola, Ludy R. [2 ]
Nguyen, Phuong-Vi [1 ]
Wang, Ethan [2 ]
Khosravi, Dara [2 ]
Taz, Azmain [2 ]
Arthur, Robert A. [3 ]
Patel, Mit [4 ]
Edara, Venkata-Viswanadh [4 ,5 ,6 ]
Foster, Stephanie L. [4 ,5 ,6 ]
Moore, Kathryn M. [4 ,5 ,6 ]
Gagne, Matthew [7 ]
Roberts-Torres, Jesmine [7 ]
Henry, Amy R. [7 ]
Godbole, Sucheta [7 ]
Douek, Daniel C. [7 ]
Rouphael, Nadine [1 ,8 ]
Suthar, Mehul S. [4 ,5 ,6 ,9 ]
Piantadosi, Anne [1 ,2 ]
机构
[1] Emory Univ, Sch Med, Dept Med, Div Infect Dis, Atlanta, GA 30322 USA
[2] Emory Univ, Sch Med, Dept Pathol & Lab Med, Woodruff Mem Res Bldg 7207A,101 Woodruff Circle, Atlanta, GA 30322 USA
[3] Emory Univ, Emory Integrated Coro Facil, Emory Integrated Computat Core, Atlanta, GA 30322 USA
[4] Emory Univ, Sch Med, Ctr Childhood Infect & Vaccines, Childrens Healthcare Atlanta,Dept Pediat, Atlanta, GA 30322 USA
[5] Emory Univ, Emory Vaccine Cantor, Atlanta, GA 30322 USA
[6] Yerkes Natl Primate Res Cantor, Atlanta, GA USA
[7] NIAID, Vaccine Res Ctr, NIH, 9000 Rockville Pike, Bethesda, MD 20892 USA
[8] Emory Univ, Sch Med, Hope Clin, Emory Vaccine Ctr, Decatur, GA 30033 USA
[9] Emory Univ, Dept Microbiol & Immunol, Atlanta, GA 30322 USA
基金
美国国家卫生研究院;
关键词
genomic surveillance; multiplex PCR; Omicron; SARS-CoV-2; vaccine;
D O I
10.1093/cid/ciac032
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We describe rapid detection of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant using targeted spike single-nucleotide polymorphism polymerase chain reaction and viral genome sequencing. This case occurred in a fully vaccinated and boosted returning traveler with mild symptoms who was identified through community surveillance rather than clinical care.
引用
收藏
页码:E350 / E353
页数:4
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