Whey-Derived Porous Carbon Scaffolds for Bone Tissue Engineering

被引：10
|
作者：
Llamas-Unzueta, Raul [1 ]
Suarez, Marta [2 ,3 ]
Fernandez, Adolfo [2 ,3 ]
Diaz, Raquel [2 ,3 ]
Montes-Moran, Miguel A. [1 ]
Menendez, J. Angel [1 ]
机构：
[1] Inst Ciencia & Tecnol Carbono INCAR CSIC, C Francisco Pintado Fe 26, Oviedo 33011, Spain
[2] Univ Oviedo UO, Nanomat & Nanotechnol Res Ctr CINN CSIC, Principado Asturias, Avda Vega 4-6, El Entrego 33940, Spain
[3] Inst Invest Sanitaria Principado Asturias, Av Roma S-N, Oviedo 33011, Spain
来源：
BIOMEDICINES | 2021年 / 9卷 / 09期
关键词：
whey; scaffolds; tissue engineering; porous carbon; biomaterials; COMPRESSIVE STRENGTH; ELASTIC PROPERTIES; CANCELLOUS BONE; HYDROXYAPATITE; FABRICATION; MICROPOROSITY; BIOMATERIALS; DENSITY; AGE;
D O I：
10.3390/biomedicines9091091
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Porous carbon structures derived from whey powders are described and evaluated as potential scaffolds in bone tissue engineering. These materials have a porosity between 48% and 58%, with a hierarchical pore size distribution ranging from 1 to 400 micrometres. Compressive strength and elastic modulus are outstanding for such a porous material, being up to three times better than those of traditional HA or TCP scaffolds with similar porosities. They also present non-cytotoxic and bioactive behavior, due to their carbon-based composition that also includes some residual mineral salts content.
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页数：15
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