The most common causative bacteria in maternal sepsis-related deaths in Japan were group A Streptococcus: A nationwide survey

被引：2

作者：

Tanaka, Hiroaki ^{[1
]}

Katsuragi, Shinji ^{[2
]}

Hasegawa, Junichi ^{[3
]}

Tanaka, Kayo ^{[1
]}

Osato, Kazuhiro ^{[1
]}

Nakata, Masahiko ^{[4
]}

Murakoshi, Takeshi ^{[5
]}

Sekizawa, Akihiko ^{[6
]}

Kanayama, Naohiro ^{[7
]}

Ishiwata, Isamu ^{[8
]}

Ikeda, Tomoaki ^{[1
]}

机构：

[1] Mie Univ, Fac Med, Dept Obstet & Gynecol, 2-174 Edobashi, Tsu, Mie, Japan

[2] Sakakibara Heart Inst, Dept Obstet & Gynecol, Tokyo, Japan

[3] St Marianna Univ, Sch Med, Dept Obstet & Gynecol, Kawasaki, Kanagawa, Japan

[4] Toho Univ, Omori Med Ctr, Dept Obstet & Gynecol, Tokyo, Japan

[5] Seirei Hamamatsu Gen Hosp, Div Perinatol, Maternal & Perinatal Care Ctr, Hamamatsu, Shizuoka, Japan

[6] Showa Univ, Dept Obstet & Gynecol, Sch Med, Tokyo, Japan

[7] Hamamatsu Univ Sch Med, Dept Obstet & Gynecol, Hamamatsu, Shizuoka, Japan

[8] Ishiwata Obstet & Gynecol Hosp, Ibaraki, Japan

来源：

JOURNAL OF INFECTION AND CHEMOTHERAPY | 2019年 / 25卷 / 01期

关键词：

Sepsis; Maternal death; Group A Streptococcus; TOXIC-SHOCK-SYNDROME; INFECTION; PREVALENCE; PYOGENES;

D O I：

10.1016/j.jiac.2018.10.004

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The present retrospective study provides an in-depth analysis of the maternal sepsis-related deaths reported in Japan, and aims to guide future care regarding maternal sepsis. This is a nationwide, retrospective, descriptive cohort study. Data were retrospectively analyzed on all maternal death cases related to sepsis reported in Japan from 2010 through 2016. A total of 7,347,727 births and 317 maternal deaths were reported during the study period. The cause of maternal death was sepsis in 24 women (7.5%). Causative bacteria were Streptococcus pyogenes (54.2%), Chlamydia psittaci (8.3%), Mycobacterium tuberculosis (8.3%), Escherichia coli (4.2%), Neisseria meningitidis (4.2%), Epstein-Barr virus (4.2%), and unknown (16.6%). In maternal death due to S. pyogenes (13 women), onset periods ware antepartum in 10 women (76.9%) and postpartum in 3 (23.1%); death within 24 h after hospital admission occurred in 7 women (53.8%); and the median time from hospital admission to death was 12 h (6-744 h). The most common causative bacteria in to maternal sepsis-related death were GAS. When encountering severe sepsis during the peripartum period, we recommend considering severe GAS infection and early intervention. (c) 2018 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

引用

页码：41 / 44

页数：4