The pan-inhibitor of VEGF receptors, GW654652 blocks growth and migration of multiple myeloma cells in the bone marrow microenvironment.

被引：0

作者：

Podar, K

Tai, YT

Carvalho, P

Catley, LP

Shringarpure, R

Burger, R

Hayashi, T

Pandite, LN

Kumar, R

Pellman, D

Hideshima, T

Chauhan, D

Anderson, KC

机构：

[1] Harvard Univ, Sch Med, Dept Med Oncol, Dana Farber Canc Inst, Boston, MA USA

[2] Harvard Univ, Sch Med, Dept Pediat Hematol & Oncol, Dana Farber Canc Inst, Boston, MA USA

[3] Glaxo Inc, Res Triangle Pk, NC 27709 USA

来源：

BLOOD | 2003年 / 102卷 / 11期

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

2563

引用

页码：692A / 692A

页数：1

共 27 条

[1] GW654652, the pan-inhibitor of VEGF receptors, blocks the growth and migration of multiple myeloma cells in the bone marrow microenvironment
Podar, K
Catley, LP
Tai, YT
Shringarpure, R
Carvalho, P
Hayashi, T
Burger, R
Schlossman, RL
Richardson, PG
Pandite, LN
Kumar, R
Hideshima, T
Chauhan, D
Anderson, KC
BLOOD, 2004, 103 (09) : 3474 - 3479
[2] Role of BAFF in adhesion and growth of human multiple myeloma cells in the bone marrow microenvironment.
Tai, YT
Li, XF
Coffey, R
Breitkreutz, I
Catley, L
Podar, K
Hideshima, T
Chauhan, D
Raje, N
Schlossman, R
Richardson, P
Munshi, NC
Anderson, KC
BLOOD, 2005, 106 (11) : 186A - 186A
[3] Arsenic trioxide inhibits growth of human multiple myeloma cells in the bone marrow microenvironment.
Hayashi, T
Hideshima, T
Akiyama, M
Richardson, P
Schlossman, RL
Chauhan, D
Waxman, S
Anderson, KC
BLOOD, 2001, 98 (11) : 375A - 375A
[4] A model for the in vitro and in vivo growth of multiple myeloma in the bone marrow microenvironment.
LeBlanc, R
Catley, L
Hideshima, T
von Schild, E
Upton, T
Anderson, KC
BLOOD, 2001, 98 (11) : 640A - 640A
[5] The VEGF receptor tyrosine kinase inhibitor PTK787 inhibits proliferation and migration of multiple myeloma cells, and reduces paracrine-mediated responses to the bone marrow microenvironment.
Lin, BK
Podar, K
Gupta, D
Tai, YT
Hideshima, T
Lentzsch, S
Davies, FE
Griffin, JD
Weissberg, E
Schlossman, RL
Richardson, PG
Wood, J
Anderson, KC
BLOOD, 2001, 98 (11) : 166A - 166A
[6] Targeting IKK inhibits multiple myeloma (MM) cell growth in the bone marrow microenvironment.
Hideshima, T
Tassone, P
Chauhan, D
Ishitsuka, K
Mitsiades, C
Raje, N
Kumar, S
Hamasaki, M
Hideshima, H
Munshi, NC
Richardson, PG
Schenkein, D
Anderson, KC
BLOOD, 2004, 104 (11) : 647A - 647A
[7] TGF-β receptor I kinase inhibitor downregulates cytokine secretion and multiple myeloma cell growth in the bone marrow microenvironment.
Hayashi, T
Hideshima, T
Podar, K
Richardson, P
Munoz, O
Hamasaki, M
Ishitsuka, K
Yasui, H
Murphy, A
McEnroe, G
Chakravarty, S
Dugar, S
Higgins, LS
Chauhan, D
Anderson, KC
BLOOD, 2004, 104 (11) : 648A - 648A
[8] The PKC-inhibitor enzastaurin inhibits MM cell growth, survival and migration in the bone marrow microenvironment.
Podar, K
Raab, MS
Abtahi, D
Tai, YT
Lin, B
Munshi, NC
Hideshima, T
Chauhan, D
Anderson, KC
BLOOD, 2005, 106 (11) : 454A - 454A
[9] TGF-β receptor I kinase inhibitor downregulates cytokine secretion and multiple myeloma cell proliferation in the bone marrow microenvironment.
Hayashi, T
Hideshima, T
Podar, K
Munoz, O
Richardson, P
Hamasaki, M
Ishitsuka, K
Murphy, A
McEnroe, G
Chakravarty, S
Dugar, S
Higgins, LS
Chauhan, D
Anderson, KC
BLOOD, 2003, 102 (11) : 388B - 388B
[10] Arsenic trioxide inhibits growth of human multiple myeloma cells in the bone marrow microenvironment
Hayashi, T
Hideshima, T
Akiyama, M
Richardson, P
Schlossman, RL
Chauhan, D
Munshi, NC
Waxman, S
Anderson, KC
MOLECULAR CANCER THERAPEUTICS, 2002, 1 (10) : 851 - 860

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