Dietary Anthocyanins against Obesity and Inflammation

被引:243
|
作者
Lee, Yoon-Mi [1 ,2 ]
Yoon, Young [1 ]
Yoon, Haelim [1 ]
Park, Hyun-Min [1 ]
Song, Sooji [1 ]
Yeum, Kyung-Jin [1 ,3 ]
机构
[1] Konkuk Univ, Div Food Biosci, Coll Biomed & Hlth Sci, Chungju Si 27478, South Korea
[2] Konkuk Univ, Nanotechnol Res Ctr, Chungju Si 27478, South Korea
[3] Konkuk Univ, Inst Biomed & Hlth Sci, Chungju Si 27478, South Korea
关键词
obesity; inflammation; anthocyanin; flavonoids; NF-KAPPA-B; OXIDATIVE STRESS; ADIPOSE-TISSUE; INSULIN-RESISTANCE; IMMUNE-SYSTEM; RAT MODEL; FAT; EXTRACT; RICH; ANTIOXIDANT;
D O I
10.3390/nu9101089
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Chronic low-grade inflammation plays a pivotal role in the pathogenesis of obesity, due to its associated chronic diseases such as type II diabetes, cardiovascular diseases, pulmonary diseases and cancer. Thus, targeting inflammation is an attractive strategy to counter the burden of obesity-induced health problems. Recently, food-derived bioactive compounds have been spotlighted as a regulator against various chronic diseases due to their low toxicity, as opposed to drugs that induce severe side effects. Here we describe the beneficial effects of dietary anthocyanins on obesity-induced metabolic disorders and inflammation. Red cabbage microgreen, blueberry, blackcurrant, mulberry, cherry, black elderberry, black soybean, chokeberry and jaboticaba peel contain a variety of anthocyanins including cyanidins, delphinidins, malvidins, pelargonidins, peonidins and petunidins, and have been reported to alter both metabolic markers and inflammatory markers in cells, animals, and humans. This review discusses the interplay between inflammation and obesity, and their subsequent regulation via the use of dietary anthocyanins, suggesting an alternative dietary strategy to ameliorate obesity and obesity associated chronic diseases.
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页数:15
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