RHEUMATOID ARTHRITIS Are ACPA-positive and ACPA-negative RA the same disease?

被引：69
|
作者：
Daha, Nina A. [1 ]
Toes, Rene E. M. [1 ]
机构：
[1] Leiden Univ, Med Ctr, Dept Rheumatol, NL-2333 ZA Leiden, Netherlands
来源：
NATURE REVIEWS RHEUMATOLOGY | 2011年 / 7卷 / 04期
关键词：
ANTIBODIES; ASSOCIATION;
D O I：
10.1038/nrrheum.2011.28
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Seemingly contrasting genetic backgrounds in anti-citrullinated-protein antibody (ACPA)-positive and ACPA-negative rheumatoid arthritis (RA) support the notion that these are in fact two distinct disease subsets, with different underlying pathogenesis, that might need tailored treatment strategies.
引用
收藏
页码：203 / 204
页数：2
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