GLOMERULAR DISEASE IN 2011 New clues to environmental influences in glomerular disease
被引:3
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作者:
Nelson, Peter J.
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Univ Washington, Med Ctr, Div Nephrol, Seattle, WA 98195 USAUniv Washington, Med Ctr, Div Nephrol, Seattle, WA 98195 USA
Nelson, Peter J.
[1
]
Alpers, Charles E.
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Univ Washington, Med Ctr, Div Nephrol, Seattle, WA 98195 USA
Univ Washington, Med Ctr, Dept Pathol, Seattle, WA 98195 USAUniv Washington, Med Ctr, Div Nephrol, Seattle, WA 98195 USA
Alpers, Charles E.
[1
,2
]
机构:
[1] Univ Washington, Med Ctr, Div Nephrol, Seattle, WA 98195 USA
[2] Univ Washington, Med Ctr, Dept Pathol, Seattle, WA 98195 USA
Research into genetic susceptibilities for proteinuric glomerular diseases has uncovered key pathogenic contributions from inheritable defects in podocytes. However, much less is known about environmental factors that may initiate or propagate podocyte injury. Seminal reports in 2011 provided new mechanistic insights into how this may occur.