Evaluation and Management of BK Virus-Associated Nephropathy Following Allogeneic Hematopoietic Cell Transplantation

被引:12
|
作者
Raval, Mihir [2 ]
Gulbis, Alison [3 ]
Bollard, Catherine [4 ]
Leen, Ann [4 ]
Chemaly, Roy [5 ]
Shpall, Elizabeth [1 ]
Lahoti, Amit [6 ]
Kebriaei, Partow [1 ]
机构
[1] Univ Texas Houston, MD Anderson Canc Ctr, Dept Stem Cell Transplantat, Houston, TX 77030 USA
[2] Univ N Dakota, Dept Internal Med, Grand Forks, ND 58201 USA
[3] Univ Texas Houston, MD Anderson Canc Ctr, Div Pharm, Houston, TX 77030 USA
[4] Texas Childrens Hosp, Baylor Coll Med, Methodist Hosp, Ctr Cell & Gene Therapy, Houston, TX 77030 USA
[5] Univ Texas Houston, MD Anderson Canc Ctr, Dept Infect Dis, Houston, TX 77030 USA
[6] Univ Texas Houston, MD Anderson Canc Ctr, Dept Nephrol, Houston, TX 77030 USA
关键词
BK virus nephropathy; Hematopoietic cell transplantation; Antiviral therapy; BONE-MARROW-TRANSPLANTATION; ONSET HEMORRHAGIC CYSTITIS; POLYOMAVIRUS BK; KIDNEY-TRANSPLANTATION; RENAL-TRANSPLANTATION; NATIVE KIDNEYS; DONOR-TYPE; RECIPIENTS; LEFLUNOMIDE; INFECTION;
D O I
10.1016/j.bbmt.2011.07.010
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
BK virus nephropathy is a common cause of graft loss in kidney transplant recipients. Cases of BK nephropathy following allogeneic hematopoietic cell transplantation (HCT) are underreported. An increased incidence of BK virus-associated nephropathy is being seen in the setting of more profound and prolonged immunosuppression following solid organ transplantation and HCT. We will review diagnostic and treatment modalities for BK-associated nephropathy following allogeneic HCT. Biol Blood Marrow Transplant 17: 1589-1593 (2011) (C) 2011 American Society for Blood and Marrow Transplantation
引用
收藏
页码:1589 / 1593
页数:5
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