Use of metformin earlier in pregnancy predicts supplemental insulin therapy in women with gestational diabetes

被引:11
|
作者
McGrath, Rachel T. [1 ,2 ,3 ]
Glastras, Sarah J. [1 ,3 ]
Hocking, Samantha [1 ,2 ,4 ]
Fulcher, Gregory R. [1 ,2 ]
机构
[1] Royal N Shore Hosp, Dept Diabet Endocrinol & Metab, Level 3,Acute Serv Bldg, Sydney, NSW 2065, Australia
[2] Univ Sydney, Northern Clin Sch, Sydney, NSW 2006, Australia
[3] Royal N Shore Hosp, Kolling Inst Med Res, Sydney, NSW, Australia
[4] Univ Sydney, Charles Perkins Ctr, Sydney, NSW 2006, Australia
关键词
Gestational diabetes; Metformin; Insulin; Glycaemic control; Perinatal outcomes;
D O I
10.1016/j.diabres.2016.04.051
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The use of metformin in gestational diabetes is safe and effective, yet some women require additional insulin therapy to achieve glycaemic targets. We found a significant association between earlier gestational age at initiation of metformin therapy and the necessity for supplemental insulin in women treated with metformin during pregnancy. (C) 2016 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:96 / 99
页数:4
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