Perineal use of talc and risk of ovarian cancer

被引：28
|
作者：
Langseth, H. [1 ]
Hankinson, S. E. [2 ,3 ]
Siemiatycki, J. [4 ]
Weiderpass, E. [1 ,5 ,6 ]
机构：
[1] Canc Registry Norway, Inst Populart Based Canc Res, NO-0310 Oslo, Norway
[2] Harvard Univ, Sch Med, Boston, MA 02115 USA
[3] Brigham & Womens Hosp, Dept Med, Channing Lab, Boston, MA 02115 USA
[4] Univ Montreal, Dept Social & Prevent Med, Montreal, PQ, Canada
[5] Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden
[6] Samfundet Folkhalsan, Helsinki, Finland
来源：
JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH | 2008年 / 62卷 / 04期
关键词：
D O I：
10.1136/jech.2006.047894
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
Ovarian cancer is one of the most common gynaecological neoplasms, especially in industrialised countries. The aetiology of the disease is not well understood, except that inherited mutations in the breast cancer genes BRCA-1 and BRCA-2 account for up to 10% of all cases, 1 and child-bearing, oral contraceptive use and breast-feeding reduce the risk. 2 Some environmental exposures, notably talc and asbestos, have been suspected as ovarian carcinogens.
引用
收藏
页码：358 / 360
页数：3
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