Does substitution of T4 with T3 plus T4 for T4 replacement improve depressive symptoms in patients with hypothyroidism?

被引：7
|
作者：
Joffe, RT
Sawka, AM
Marriott, MJ
MacQueen, GM
Gernstein, HC
机构：
[1] Univ Med & Dent New Jersey, New Jersey Med Sch, Dept Psychiat, Newark, NJ 07103 USA
[2] Univ Med & Dent New Jersey, New Jersey Med Sch, Dept Med, Div Endocrinol & Metab, Newark, NJ 07103 USA
[3] McMaster Univ, Dept Psychiat, Hamilton, ON, Canada
[4] McMaster Univ, Dept Behav Sci, Hamilton, ON, Canada
来源：
BIOBEHAVIORAL STRESS RESPONSE: PROTECTIVE AND DAMAGING EFFECTS | 2004年 / 1032卷
关键词：
thyroxine; triiodothyronine; depression;
D O I：
10.1196/annals.1314.040
中图分类号：
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号：
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要：
Substitution of T4 with T3 for T4 replacement in patients with hypothyroidism was undertaken using a randomized placebo controlled study design. Forty individuals were included who had depressive symptoms on stable doses of levothyroxine. Combined T4 plus T3 did not have a significantly different effect on mood and well-being scores than did T4 alone.
引用
收藏
页码：287 / 288
页数：2
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