TELOMERASE-SPECIFIC ONCOLYTIC ADENOVIRUS ARMED WITH WILD-TYPE P53 GENE (CGCT-04) EFFICIENTLY INDUCES APOPTOSIS IN HUMAN CANCER CELLS

被引:0
|
作者
Yamasaki, Yasumoto [1 ]
Onimatsu, Hideki [2 ]
Hashimoto, Yuuri [2 ]
Kojima, Toru [1 ]
Tazawa, Hiroshi [3 ]
Kagawa, Shunsuke [1 ,3 ]
Mizuguchi, Hiroyuki [4 ]
Urata, Yasuo [2 ]
Tanaka, Noriaki [1 ]
Fujiwara, Toshiyoshi [1 ,3 ]
机构
[1] Okayama Univ, Grad Sch, Dept Surg, Okayama, Japan
[2] Oncolys Biopharma Inc, Tokyo, Japan
[3] Okayama Univ Hosp, Ctr Gene & Cell Therapy, Okayama, Japan
[4] Osaka Univ, Dept Biochem & Mol Biol, Grad Sch Pharmaceut Sci, Osaka, Japan
来源
JOURNAL OF GENE MEDICINE | 2010年 / 12卷 / 12期
关键词
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
引用
收藏
页码:1035 / 1035
页数:1
相关论文
共 50 条
  • [1] Telomerase-specific oncolytic adenovirus armed with wild-type p53 gene (CGCT-04) efficiently induces apoptosis in human cancer cells
    Yamasaki, Yasumoto
    Onimatsu, Hideki
    Hashimoto, Yuuri
    Kojima, Toru
    Tazawa, Hiroshi
    Kagawa, Shunsuke
    Mizuguchi, Hiroyuki
    Urata, Yasuo
    Tanaka, Noriaki
    Fujiwara, Toshiyoshi
    CANCER RESEARCH, 2009, 69
  • [2] Boosting immunity against pancreatic cancer by OBP-702 (Pfifteloxin), telomerase-specific replicative adenovirus armed with wild-type p53 gene
    Araki, Hiroyuki
    Tazawa, Hiroshi
    Fushimi, Takuro
    Nishiyama, Takeyoshi
    Kikuchi, Satotu
    Kuroda, Shinji
    Yoshida, Ryuichi
    Kishimoto, Hiroyuki
    Nishizaki, Masahiko
    Urata, Yasuo
    Kagawa, Shunsuke
    Fujiwara, Toshiyoshi
    CANCER RESEARCH, 2019, 79 (13)
  • [3] Scoring system to predict antitumor effects of p53-armed telomerase-specific oncolytic adenovirus
    Sugimoto, Ryoma
    Kuroda, Shinji
    Yoshida, Yusuke
    Sakamoto, Masaki
    Hamada, Yuki
    Yagi, Chiaki
    Hashimoto, Masashi
    Kakiuchi, Yoshihiko
    Kikuchi, Satoru
    Kagawa, Shunsuke
    Tazawa, Hiroshi
    Urata, Yasuo
    Fujiwara, Toshiyoshi
    CANCER SCIENCE, 2023, 114 : 2210 - 2210
  • [4] Adenovirus-mediated wild-type p53 gene transfer and overexpression induces apoptosis of human glioma cells independent of endogenous p53 status
    Li, HW
    Lochmuller, H
    Yong, VW
    Karpati, G
    Nalbantoglu, J
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 1997, 56 (08): : 872 - 878
  • [5] Wild-Type p53 Regulates Apoptosis of Human Breast Cancer Cells
    Zhang, Xuliang
    Yu, Guozheng
    Cai, Lei
    Jian, Ming
    Cai, Lixia
    Xu, Dong
    DISCOVERY MEDICINE, 2024, 36 (191) : 2445 - 2453
  • [6] Adenovirus-mediated wild-type p53 gene transfer induces apoptosis and inhibits proliferation of human uveal melanoma cells.
    Rota, R
    Cirielli, C
    Blasi, MA
    Martinotti, S
    Toniato, E
    Capogrossi, M
    Procopio, A
    Balestrazzi, E
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 1996, 37 (03) : 5187 - 5187
  • [7] Adenovirus-mediated wild-type p53 tumor suppressor gene therapy induces apoptosis and suppresses growth of human pancreatic cancer
    Bouvet, M
    Bold, RJ
    Lee, J
    Evans, DB
    Abbruzzese, JL
    Chiao, PJ
    McConkey, DJ
    Chandra, J
    Chada, S
    Fang, BL
    Roth, JA
    ANNALS OF SURGICAL ONCOLOGY, 1998, 5 (08) : 681 - 688
  • [8] Adenovirus-mediated transfer of a wild-type p53 gene and induction of apoptosis in cervical cancer
    Hamada, K
    Alemany, R
    Zhang, WW
    Hittelman, WN
    Lotan, R
    Roth, JA
    Mitchell, MF
    CANCER RESEARCH, 1996, 56 (13) : 3047 - 3054
  • [9] Treatment of radioresistant stem-like esophageal cancer cells by an apoptotic gene-armed,telomerase-specific oncolytic adenovirus
    Zhang, Xiaochun
    Komaki, Ritsuko
    Wang, Li
    Fang, Bingliang
    Chang, Joe Y.
    CLINICAL CANCER RESEARCH, 2008, 14 (09) : 2813 - 2823
  • [10] Gene therapy of malignant gliomas: Adenovirus-mediated wild-type p53 expression induces widespread apoptosis of human glioma cells independently of endogenous p53 status
    Li, HW
    Lochmuller, H
    Seth, P
    Karpati, G
    Nalbantoglu, J
    NEUROLOGY, 1997, 48 (03) : 1026 - 1026