Induction of Immune Tolerance through an Epitope-Specific Vaccine Induces Clinical Amelioration in Patients with Rheumatoid Arthritis

被引：0

作者：

Chan, Jin Hui Sherlynn ^{[1
]}

van den Broek, Theodorus ^{[2
]}

Leong, Jing Yao ^{[1
]}

Rossetti, Maura ^{[3
]}

Spreafico, Roberto ^{[4
]}

Albani, Salvatore ^{[1
,5
]}

机构：

[1] Duke NUS Med Sch, STIIC, Singapore, Singapore

[2] Univ Med Ctr Utrecht, Utrecht, Netherlands

[3] Univ Calif Los Angeles, Los Angeles, CA USA

[4] Synthet Genom, La Jolla, CA USA

[5] KK Womens & Childrens Hosp, Singapore, Singapore

来源：

ARTHRITIS & RHEUMATOLOGY | 2017年 / 69卷

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

1462

引用

页数：2

共 50 条

[1] REACTIVATION OF IMMUNE CHECKPOINTS BY AN EPITOPE-SPECIFIC VACCINE REINSTATES TOLEROGENIC PATHWAYS AND INDUCES CLINICAL AMELIORATION IN PATIENTS WITH RHEUMATOID ARTHRITIS
Chan, J. H. S.
van den Broek, T.
Leong, J. Y.
Rossetti, M.
Spreafico, R.
Albani, S.
ANNALS OF THE RHEUMATIC DISEASES, 2018, 77 : 977 - 977
[2] Epitope-specific immunotherapy induces immune deviation of proinflammatory T cells in rheumatoid arthritis
Prakken, BJ
Samodal, R
Le, TD
Giannoni, F
Yung, GP
Scavulli, J
Amox, D
Roord, S
de Kleer, I
Bonnin, D
Lanza, P
Berry, C
Massa, M
Billetta, R
Albani, S
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (12) : 4228 - 4233
[3] Epitope-specific immunotherapy in rheumatoid arthritis
Albani, S
Bathon, J
Belardi, F
Berry, C
Dennehey, C
Firestein, G
Genovese, M
Kavanaugh, A
Martinez, A
Matteson, E
Molitor, J
Posever, J
Santana, E
Samodal, R
Schiff, M
IMMUNOLOGY, 2005, 116 : 43 - 44
[4] Kinetics of immune tolerization in a clinical trial on epitope-specific therapy in rheumatoid arthritis (RA)
Koffeman, Eva
Amox, Diane
Tremoulet, Adriana
Keogh, Elissa
Zeiseniss, Peter
Gosch, Courtney
Friend, Samantha
Zhang, Xiao
Cutter, Gary
Albani, Salvatore
CLINICAL IMMUNOLOGY, 2007, 123 : S96 - S97
[5] Epitope-specific tolerance induction with an engineered immunoglobulin
Zambidis, E. T.
Scott, D. W.
Proceedings of the National Academy of Sciences of the United States of America, 93 (10):
[6] Epitope-specific tolerance induction with an engineered immunoglobulin
Zambidis, ET
Scott, DW
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (10) : 5019 - 5024
[7] Epitope-specific therapy in rheumatoid arthritis, phase 2 clinical and immunological results.
Koffeman, Eva
Amox, Diane
Genovese, Mark
Schiff, Michael
Dennehey, Carolyn
Posever, James
Belardi, Francis
Santana, Ernesto
Molitor, Jerry
Bathon, Joan
Matteson, Eric
Kivitz, Allan
Berry, Charles
Keogh, Elissa
Yung, Gisella Puga
Tremoulet, Adriana
Zieseniss, Peter
Gosch, Courtney
Friend, Samantha
Martinez, Alex
Le, Tho
Samodal, Rodrigo
Kavanaugh, Arthur
Sriuma, Jearanai
Zhang, Xiao
Prakken, Berent
Cutter, Gary
Albani, Salvatore
CLINICAL IMMUNOLOGY, 2006, 119 : S4 - S5
[8] Phase II trial of epitope-specific immunotherapy in rheumatoid arthritis.
Albani, S
Tremoulet, A
Genovese, M
Schiff, M
Dennehey, C
Posever, J
Belardi, F
Santana, E
Molitor, J
Bathon, J
Matteson, E
Kavanaugh, A
Martinez, A
Amox, D
Keogh, E
Berry, C
Cutter, G
Puga-Yung, G
Gosch, C
Koffeman, E
Friend, S
Zieseniss, P
Samodal, R
Le, T
ARTHRITIS AND RHEUMATISM, 2005, 52 (12): : 4059 - 4059
[9] Induction of immune tolerance in the treatment of rheumatoid arthritis
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Berent Prakken
Nature Reviews Rheumatology, 2011, 7 : 272 - 281
[10] Induction of immune tolerance in the treatment of rheumatoid arthritis
Albani, Salvatore
Koffeman, Eva C.
Prakken, Berent
NATURE REVIEWS RHEUMATOLOGY, 2011, 7 (05) : 273 - 282

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