Long-term Storage and Cannabis Oil Stability

The paper presents the results of an experimental study regarding the stability of cannabis oil during its long-term storage in different conditions. The content of major cannabinoids, namely tetrahydrocannabinol (Delta(9)-THC), cannabinol (CBN), and cannabidiol (CBD) contained in two batch samples of cannabis oil seizures made by criminal prosecution authorities from Romania was measured during their storage over a period of four years in darkness at 4 degrees C and in laboratory light at 22 degrees C. The results revealed a steadily decay of Delta(9)-THC over the entire storage period from a very high initial content up to a relatively low final content. A slight difference regarding the degree of decay of Delta(9)-THC between the two storage conditions was recorded, meaning that this is more pronounced when the samples were exposed to light at 22 degrees C. The same trend was recorded for CBD. As expected, the content of CBN increases during storage and the increase is higher when the samples were exposed to light at 22 degrees C.