The HOX gene cluster in the bivalve mollusc Mytilus galloprovincialis

被引:12
|
作者
Pérez-Parallé, ML [1 ]
Carpintero, P [1 ]
Pazos, AJ [1 ]
Abad, M [1 ]
Sánchez, JL [1 ]
机构
[1] Univ Santiago de Compostela, Inst Acuicultura, Dept Bioquim & Biol Mol, Lab Biol Mol & Desarrollo, Santiago De Compostela 15782, Spain
关键词
deformed; homeobox; Mytilus galloprovincialis; proboscipedia; sex comb reduced; zerknullt;
D O I
10.1007/s10528-005-6780-4
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The clustered Hox genes play a central role in the regulation of development in bilaterian animals. In this study, we analyzed the homeobox-containing genes in a bivalve mollusc, the mussel Mytilus galloprovincialis, an unsegmented spiralian lophotrochozoan. We isolated and characterized four Hox cluster genes using the polymerase chain reaction with specific primers. Molecular alignments and phylogenetic analysis indicate that these mussel genes are homologs of the anterior group (pb ortholog), paralog group 3, and central group (PG4/Dfd and PG5/Scr) genes. The putative homeodomain sequences were designated Mgox1, Mgox2, Mgox3, and Mgox4.
引用
收藏
页码:417 / 424
页数:8
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