Nasopharyngeal Carcinoma Presenting With Horner Syndrome and Carotid-Sinus Syncope

Introduction: Nasopharyngeal carcinoma can present with different neurological signs and findings. In this paper, we report a patient presenting with Horner syndrome and syncopal episodes who was finally diagnosed with nasopharyngeal carcinoma. Case Report: A 56-year-old man presented with a history of slowly progressive right upper-eyelid droop for the last 1.5 months and episodes of loss of consciousness. After detailed clinical and laboratory examinations, the patient had the final diagnosis of metastatic nasopharyngeal carcinoma. Conclusions: This is the first case with nasopharyngeal carcinoma presenting with both Horner syndrome and carotid-sinus syncope. The mechanism of Horner syndrome and the syncopal episodes and their relation with the lesion location are discussed.