The drug development process: from target discovery to the clinic

被引:2
|
作者
Newell, DR [1 ]
机构
[1] Univ Newcastle, No Inst Canc Res, Newcastle Upon Tyne, Tyne & Wear, England
关键词
analogue development; cytotoxic drugs; imatinib; targeted therapy; trastuzumab;
D O I
10.7861/clinmedicine.3-4-323
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:323 / 326
页数:4
相关论文
共 50 条
  • [1] Therapeutic target discovery and drug development in cancer stem cells for leukemia and lymphoma: from bench to the clinic
    Laranjeira, Angelo B. A.
    Yang, Sherry X.
    [J]. EXPERT OPINION ON DRUG DISCOVERY, 2016, 11 (11) : 1071 - 1080
  • [2] Biomarkers in Drug Discovery and Development: From Target Identification to Drug Marketing
    Ayre, Anita Pandurang
    Soni, Dimple
    Shimpi, Sheetal
    [J]. INTERNATIONAL JOURNAL OF PHARMACEUTICAL AND PHYTOPHARMACOLOGICAL RESEARCH, 2011, 1 (01): : 28 - 34
  • [3] FROM DISCOVERY TO MARKET - THE NEW DRUG DEVELOPMENT PROCESS
    LEE, WA
    BISCHOFBERGER, N
    [J]. CHEMICKE LISTY, 1995, 89 (01): : 22 - 29
  • [4] From target discovery to clinical drug development with human genetics
    Trajanoska, Katerina
    Bherer, Claude
    Taliun, Daniel
    Zhou, Sirui
    Richards, J. Brent
    Mooser, Vincent
    [J]. NATURE, 2023, 620 (7975) : 737 - 745
  • [5] From target discovery to clinical drug development with human genetics
    Katerina Trajanoska
    Claude Bhérer
    Daniel Taliun
    Sirui Zhou
    J. Brent Richards
    Vincent Mooser
    [J]. Nature, 2023, 620 : 737 - 745
  • [6] Biomarkers in drug discovery and development: From target identification through drug marketing
    Colburn, WA
    [J]. JOURNAL OF CLINICAL PHARMACOLOGY, 2003, 43 (04): : 329 - 341
  • [7] Target profiling aiding the drug discovery process
    Godl, K.
    Wissing, J.
    Brehmer, D.
    Blencke, S.
    Klebl, B.
    Daub, H.
    Mueller, G.
    [J]. MOLECULAR & CELLULAR PROTEOMICS, 2005, 4 (08) : S364 - S364
  • [8] Advancing the Drug Discovery and Development Process
    Nicolaou, K. C.
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2014, 53 (35) : 9128 - 9140
  • [9] Morphogenics as a tool for target discovery and drug development
    Nicolaides, NC
    Ebel, W
    Kline, B
    Chao, QM
    Routhier, E
    Sass, PM
    Grasso, L
    [J]. TUMOR PROGRESSION AND THERAPEUTIC RESISTANCE, 2005, 1059 : 86 - 96
  • [10] The importance of target validation in drug discovery and development
    Lowe, John A.
    Jones, Phil
    Wilson, David M.
    [J]. CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT, 2009, 12 (05) : 581 - 584