Development of a viscosity sensitive fluorescent probe for real-time monitoring of mitochondria viscosity

被引：60
|
作者：
Zhou, Kai [1 ]
Ren, Mingguang [1 ]
Deng, Beibei [1 ]
Lin, Weiying [1 ]
机构：
[1] Univ Jinan, Inst Fluorescent Probes Biol Imaging, Sch Chem & Chem Engn, Sch Mat Sci & Engn, Jinan 250022, Shandong, Peoples R China
来源：
NEW JOURNAL OF CHEMISTRY | 2017年 / 41卷 / 20期
关键词：
LIVING CELLS; OPTICAL-PROPERTIES; IMAGING VISCOSITY; MOLECULAR ROTORS; RATIONAL DESIGN; IN-VIVO; MEMBRANE; SENSOR; DYES;
D O I：
10.1039/c7nj02270k
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Using hemicyanine and carbazole as an acceptor and a donor, respectively, we designed and synthesized two new mitochondrial-targeted fluorescent viscosity probes (MHC-V1 and MHC-V2). The new probes were membrane-permeable and suitable for visualization of the changes of viscosity within the mitochondria of living cells.
引用
收藏
页码：11507 / 11511
页数：5
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