The association of frontal fibrosing alopecia (FFA) and lichen planus pigmentosus (LPPigm) is rare. Prior reports suggest that FFA and LPPigm are on the same spectrum of disease, and a diagnosis of LPPigm may predict the future development of FFA. We aim to further characterize the association between FFA and LPPigm by reviewing the clinical cases of seven African American women. Seven patients with FFA were diagnosed clinically by recession of frontotemporal hairline and confirmed by histopathologic examination showing lymphocyte-mediated cicatricial alopecia. LPPigm was diagnosed by clinical evaluation alone based on the characteristic morphology, color, and distribution of the lesions. It is difficult to distinguish whether halted progression of FFA was due to the success of the treatment regimen or spontaneous stabilization of disease over time. Our case series supports the theory that FFA and LPPigm likely exist on the same spectrum of disease. Our observations demonstrate a likely positive correlation between FFA and LPPigm.
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Univ Calif San Francisco, Dept Dermatol, San Francisco, CA 94143 USAUniv Calif San Francisco, Dept Dermatol, San Francisco, CA 94143 USA
Berliner, Jacqueline Goulart
McCalmont, Timothy H.
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Univ Calif San Francisco, Dept Dermatol, San Francisco, CA 94143 USA
Univ Calif San Francisco, Dept Pathol, San Francisco, CA 94143 USAUniv Calif San Francisco, Dept Dermatol, San Francisco, CA 94143 USA
McCalmont, Timothy H.
Price, Vera H.
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Univ Calif San Francisco, Dept Dermatol, San Francisco, CA 94143 USAUniv Calif San Francisco, Dept Dermatol, San Francisco, CA 94143 USA
Price, Vera H.
Berger, Timothy G.
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Univ Calif San Francisco, Dept Dermatol, San Francisco, CA 94143 USAUniv Calif San Francisco, Dept Dermatol, San Francisco, CA 94143 USA
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Univ KwaZulu Natal, Nelson R Mandela Sch Med, Dept Dermatol, ZA-4013 Durban, South AfricaUniv KwaZulu Natal, Nelson R Mandela Sch Med, Dept Dermatol, ZA-4013 Durban, South Africa
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George Washington Univ, Sch Med & Hlth Sci, Dept Dermatol, Washington, DC 20052 USAGeorge Washington Univ, Sch Med & Hlth Sci, Dept Dermatol, Washington, DC 20052 USA
Whiting, Cleo
Friedman, Adam
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George Washington Univ, Sch Med & Hlth Sci, Dept Dermatol, Washington, DC 20052 USAGeorge Washington Univ, Sch Med & Hlth Sci, Dept Dermatol, Washington, DC 20052 USA
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Corporal Michael J Crescenz VAMC, Philadelphia, PA 19104 USA
Univ Penn, Philadelphia, PA 19104 USACorporal Michael J Crescenz VAMC, Philadelphia, PA 19104 USA
Kushner, Carolyn J.
Concha, Josef Symon S.
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Corporal Michael J Crescenz VAMC, Philadelphia, PA 19104 USA
Univ Penn, Philadelphia, PA 19104 USACorporal Michael J Crescenz VAMC, Philadelphia, PA 19104 USA
Concha, Josef Symon S.
Pearson, David R.
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Corporal Michael J Crescenz VAMC, Philadelphia, PA 19104 USA
Univ Penn, Philadelphia, PA 19104 USA
Univ Minnesota, Minneapolis, MN USACorporal Michael J Crescenz VAMC, Philadelphia, PA 19104 USA
Pearson, David R.
Werth, Victoria P.
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Corporal Michael J Crescenz VAMC, Philadelphia, PA 19104 USA
Univ Penn, Philadelphia, PA 19104 USACorporal Michael J Crescenz VAMC, Philadelphia, PA 19104 USA