Kinetic Study of Asymmetric Hydrogenation of α, β-Unsaturated Carboxylic Acid Over Cinchona-Modified Pd/Al2O3 Catalyst

被引：11

作者：

Tan, Shuai ^{[1
]}

Monnier, John R. ^{[1
]}

Williams, Christopher T. ^{[1
]}

机构：

[1] Univ S Carolina, Dept Chem Engn, Columbia, SC 29208 USA

来源：

TOPICS IN CATALYSIS | 2012年 / 55卷 / 7-10期

基金：

美国国家科学基金会;

关键词：

Enantioselective hydrogenation; Cinchonidine; Unsaturated carboxylic acid; Palladium; ENANTIO-SELECTIVE HYDROGENATION; MODIFIED PD CATALYSTS; ENANTIOSELECTIVE HYDROGENATION; (E)-ALPHA-PHENYLCINNAMIC ACID; MODIFIED PALLADIUM; 2-METHYL-2-PENTENOIC ACID; MODIFIED PD/TIO2; FINE CHEMICALS; PLATINUM; TEMPERATURE;

D O I：

10.1007/s11244-012-9811-5

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The enantioselective hydrogenation of 2-methyl-2-pentenoic acid (MPeA) over cinchonidine-modified 5 wt % Pd/gamma-Al2O3 catalyst has been studied. The reaction exhibited a strong solvent-dependent behavior in terms of activity. The presence of cinchonidine does not affect the reaction order with respect to either acid or H-2 pressure, but has a significant inhibiting effect on the reaction rate.

引用

页码：512 / 517

页数：6

共 50 条

[1] Kinetic Study of Asymmetric Hydrogenation of α, β-Unsaturated Carboxylic Acid Over Cinchona-Modified Pd/Al2O3 Catalyst
Shuai Tan
John R. Monnier
Christopher T. Williams
[J]. Topics in Catalysis, 2012, 55 : 512 - 517
[2] Asymmetric hydrogenation of racemic 2-fluorocyclohexanone over cinchona modified Pt/Al2O3 catalyst
Szori, Kornel
Szollosi, Gyorgy
Bartok, Mihaly
[J]. JOURNAL OF CATALYSIS, 2006, 244 (02) : 255 - 259
[3] Unexpected Inversion in Enantioselectivity in the Hydrogenation N-acetyl Dehydrophenylalanine Methyl Ester using Cinchona-Modified Pd/Al2O3 catalyst
Nichola J. Colston
Richard P. K. Wells
Peter B. Wells
Graham J. Hutchings
[J]. Catalysis Letters, 2005, 103 : 117 - 120
[4] Unexpected inversion in enantioselectivity in the hydrogenation N-acetyl dehydrophenylalanine methyl ester using cinchona-modified Pd/Al2O3 catalyst
Colston, NJ
Wells, RPK
Wells, PB
Hutchings, GJ
[J]. CATALYSIS LETTERS, 2005, 103 (1-2) : 117 - 120
[5] New synthesis of optically active α-arylpropanoic acid:: The asymmetric hydrogenation of atropic acid over cinchona-modified Pd/Fe2O3 catalysts
Ma, HZ
Wang, B
Shi, QZ
[J]. SYNTHETIC COMMUNICATIONS, 2003, 33 (02) : 175 - 182
[6] Heterogeneous asymmetric reactions Part 17.: Asymmetric hydrogenation of 2-methyl-2-pentenoic acid over cinchona modified Pd/Al2O3 catalysts
Kun, I
Török, B
Felföldi, K
Bartók, M
[J]. APPLIED CATALYSIS A-GENERAL, 2000, 203 (01) : 71 - 79
[7] BENZENE HYDROGENATION OVER A PD/AL2O3 CATALYST
VANNICE, MA
NEIKAM, WC
[J]. JOURNAL OF CATALYSIS, 1971, 23 (03) : 401 - &
[8] Kinetic studies of the enantioselective hydrogenation of ethyl pyruvate catalyzed by a cinchona modified Pt/Al2O3 catalyst
Blaser, HU
Jalett, HP
Garland, M
Studer, M
Thies, H
Wirth-Tijani, A
[J]. JOURNAL OF CATALYSIS, 1998, 173 (02) : 282 - 294
[9] Kinetic Studies of the Enantioselective Hydrogenation of Ethyl Pyruvate Catalyzed by a Cinchona Modified Pt/Al2O3 Catalyst
Blaser, H.-U.
Jalett, H.-P.
Garland, M.
Studer, M.
[J]. Journal of Catalysis, 173 (02):
[10] Dynamic kinetic resolution over Cinchona-modified platinum catalyst:: Hydrogenation of racemic ethyl 2-fluoroacetoacetate
Szöri, K
Szöllösi, G
Bartók, M
[J]. ADVANCED SYNTHESIS & CATALYSIS, 2006, 348 (4-5) : 515 - 522

← 1 2 3 4 5 →