Assessment of therapeutic options for reducing alkali burn-induced corneal neovascularization and inflammation

被引：31

作者：

Bakunowicz-Lazarczyk, Alina ^{[1
]}

Urban, Beata ^{[1
]}

机构：

[1] Med Univ Bialystok, Dept Pediat Ophthalmol & Strabismus, Waszyngtona 17, PL-15274 Bialystok, Poland

来源：

ADVANCES IN MEDICAL SCIENCES | 2016年 / 61卷 / 01期

关键词：

Corneal neovascularization; Alkali burn; Treatment; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; MICROVASCULAR ENDOTHELIAL-CELLS; MOLECULAR-WEIGHT HEPARIN; ACTIVATED RECEPTOR-GAMMA; MESENCHYMAL STEM-CELLS; OCULAR CHEMICAL BURNS; BEVACIZUMAB AVASTIN; ASCORBIC-ACID; GROWTH-FACTOR; RAT MODEL;

D O I：

10.1016/j.advms.2015.10.003

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

This article aims to review and provide the current knowledge of the possibilities of topical treatment of corneal neovascularization due to alkali burns, evidenced by laboratory experiments, in vitro studies, and clinical trials published in the specialized literature. Authors present clinically relevant treatment of corneal neovascularization used in clinical practice, potential antiangiogenic topical therapeutics against corneal neovascularization, which are under investigation, and anti-angiogenic gene-therapy. (C) 2015 Medical University of Bialystok. Published by Elsevier Sp. z o.o. All rights reserved.

引用

页码：101 / 112

页数：12

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