Psoriasis and psoriatic arthritis induced in a patient treated with infliximab for Crohn's disease

被引:11
|
作者
Tichy, Martin, Jr. [1 ]
Tichy, Martin [2 ]
Kopova, Renata [1 ]
Sternbersky, Jan [1 ]
Ditrichova, Dagmar [1 ]
机构
[1] Palacky Univ, Fac Med & Dent, Univ Hosp, Dept Dermatol & Venereol, Olomouc 77520, Czech Republic
[2] Palacky Univ, Fac Med & Dent, Univ Hosp, Dept Pathol, Olomouc 77520, Czech Republic
关键词
adverse reaction; Crohn's disease; infliximab; psoriasis; psoriatic arthritis; SERIES;
D O I
10.3109/09546634.2010.521811
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
The induction of psoriasis as a side effect of treatment with TNF-alpha inhibitors is one of a few rare complications of treatment, the pathogenic mechanism of which has not yet been completely clarified. The clinical presentation of these reactions may show the typical characteristics of psoriasis, palmoplantar pustulosis and psoriasiform exanthema; the individual variations of which may combine to give different presentations in individual patients. We present the case of a patient who, after administration of infliximab indicated for Crohn's disease, developed not only skin manifestations but also those of psoriatic arthritis.
引用
收藏
页码:208 / 211
页数:4
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