Targeted disruption of PI3K/Akt/mTOR signaling pathway induces cell cycle arrest, apoptosis, and autophagy, and inhibits inflammation, invasion and angiogenesis of OSCC cells.

被引：0
|
作者：
Aggarwal, Sadhna [1 ]
John, Sarah [1 ]
Sharma, Suresh C. [1 ]
Das, Satya N. [1 ]
机构：
[1] AIIMS, Delhi, India
来源：
CANCER IMMUNOLOGY RESEARCH | 2020年 / 8卷 / 04期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
A60
引用
收藏
页码：66 / 67
页数：2
相关论文
共 50 条
  • [1] Targeted disruption of PI3K/Akt/mTOR signaling pathway induces cell cycle arrest, apoptosis, autophagy, and inhibits inflammation, invasion, and angiogenesis of OSCC cells
    Aggarwal, Sadhna
    John, Sarah
    Das, Satya N.
    Sharma, Suresh C.
    MOLECULAR CANCER RESEARCH, 2020, 18 (10) : 42 - 42
  • [2] Danusertib Induces Apoptosis, Cell Cycle Arrest, and Autophagy but Inhibits Epithelial to Mesenchymal Transition Involving PI3K/Akt/mTOR Signaling Pathway in Human Ovarian Cancer Cells
    Zi, Dan
    Zhou, Zhi-Wei
    Yang, Ying-Jie
    Huang, Lin
    Zhou, Zun-Lun
    He, Shu-Ming
    He, Zhi-Xu
    Zhou, Shu-Feng
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2015, 16 (11) : 27228 - 27251
  • [3] Pectolinarigenin Induced Cell Cycle Arrest, Autophagy, and Apoptosis in Gastric Cancer Cell via PI3K/AKT/mTOR Signaling Pathway
    Lee, Ho Jeong
    Saralamma, Venu Venkatarame Gowda
    Kim, Seong Min
    Ha, Sang Eun
    Raha, Suchismita
    Lee, Won Sup
    Kim, Eun Hee
    Lee, Sang Joon
    Heo, Jeong Doo
    Kim, Gon Sup
    NUTRIENTS, 2018, 10 (08)
  • [4] Targeted inhibition of the PI3K/AKT/mTOR pathway by (+)-anthrabenzoxocinone induces cell cycle arrest, apoptosis, and autophagy in non-small cell lung cancer
    Li, Xiao-Qian
    Cheng, Xiao-Ju
    Wu, Jie
    Wu, Kai-Feng
    Liu, Tie
    CELLULAR & MOLECULAR BIOLOGY LETTERS, 2024, 29 (01)
  • [5] Mahanine induces apoptosis, cell cycle arrest, inhibition of cell migration, invasion and PI3K/AKT/mTOR signalling pathway in glioma cells and inhibits tumor growth in vivo
    Chen, Maohua
    Yin, Xiangqian
    Lu, Chuan
    Chen, Xiandong
    Ba, Huajun
    Cai, Jianyong
    Sun, Jun
    CHEMICO-BIOLOGICAL INTERACTIONS, 2019, 299 : 1 - 7
  • [6] Honokiol induces autophagy and apoptosis of osteosarcoma through PI3K/Akt/mTOR signaling pathway
    Li, Zhiquan
    Dong, Hui
    Li, Mo
    Wu, Yaoping
    Liu, Yanwu
    Zhao, Yinan
    Chen, Xiaochao
    Ma, Minliang
    MOLECULAR MEDICINE REPORTS, 2018, 17 (02) : 2719 - 2723
  • [7] Plumbagin induces Ishikawa cell cycle arrest, autophagy, and apoptosis via the PI3K/Akt signaling pathway in endometrial cancer
    Zhang, Xiangsheng
    Kan, Huan
    Liu, Yun
    Ding, Wu
    FOOD AND CHEMICAL TOXICOLOGY, 2021, 148
  • [8] Oxymatrine induces cell cycle arrest and apoptosis and suppresses the invasion of human glioblastoma cells through the EGFR/PI3K/Akt/mTOR signaling pathway and STAT3
    Dai, Zhibo
    Wang, Ligang
    Wang, Xiaoxiong
    Zhao, Boxian
    Zhao, Wenyang
    Bhardwaj, Shashank Singh
    Ye, Junyi
    Yin, Zhiqin
    Zhang, Jun
    Zhao, Shiguang
    ONCOLOGY REPORTS, 2018, 40 (02) : 867 - 876
  • [9] Dauricine inhibits viability and induces cell cycle arrest and apoptosis via inhibiting the PI3K/Akt signaling pathway in renal cell carcinoma cells
    Zhang, Shuwei
    Ren, Yu
    Qiu, Jianxin
    MOLECULAR MEDICINE REPORTS, 2018, 17 (05) : 7403 - 7408
  • [10] Rottlerin induces autophagy and apoptosis in prostate cancer stem cells via PI3K/Akt/mTOR signaling pathway
    Kumar, Dhruv
    Shankar, Sharmila
    Srivastava, Rakesh K.
    CANCER LETTERS, 2014, 343 (02) : 179 - 189
12345