Effect of gentamicin dosing interval on efficacy of penicillin or ceftriaxone treatment of experimental endocarditis due to penicillin-susceptible, ceftriaxone-tolerant viridans group streptococci

被引：5
|
作者：
Brandt, CM
Warner, CB
Rouse, MS
Steckelberg, JM
Wilson, WR
机构：
[1] MAYO CLIN & MAYO FDN,DIV INFECT DIS,ROCHESTER,MN 55905
[2] MAYO CLIN & MAYO FDN,INFECT DIS RES LAB,ROCHESTER,MN 55905
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1996年 / 40卷 / 12期
关键词：
D O I：
10.1128/AAC.40.12.2901
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The efficacy of ceftriaxone or penicillin alone or combined with gentamicin at different dosing intervals was evaluated in experimental endocarditis due to a penicillin-susceptible, ceftriaxone-tolerant strain of Streptococcus sanguis I. The difference between monotherapy with ceftriaxone and procaine penicillin approached statistical significance (P = 0.052). Ceftriaxone combined with gentamicin administered as a single daily dose was less effective than was procaine penicillin combined with gentamicin administered in a single daily dose or in three divided doses.
引用
收藏
页码：2901 / 2903
页数：3
相关论文
共 14 条
  • [1] PARENTERAL SPARFLOXACIN COMPARED WITH CEFTRIAXONE IN TREATMENT OF EXPERIMENTAL ENDOCARDITIS DUE TO PENICILLIN-SUSCEPTIBLE AND PENICILLIN-RESISTANT STREPTOCOCCI
    ENTENZA, JM
    BLATTER, M
    GLAUSER, MP
    MOREILLON, P
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1994, 38 (12) : 2683 - 2688
  • [2] Ceftriaxone once daily for four weeks compared with ceftriaxone plus gentamicin once daily for two weeks for treatment of endocarditis due to penicillin-susceptible streptococci
    Sexton, DJ
    Tenenbaum, MJ
    Wilson, WR
    Steckelberg, JM
    Tice, AD
    Gilbert, D
    Dismukes, W
    Drew, RH
    Durack, DT
    [J]. CLINICAL INFECTIOUS DISEASES, 1998, 27 (06) : 1470 - 1474
  • [3] TREATMENT OF ENDOCARDITIS DUE TO PENICILLIN-SUSCEPTIBLE STREPTOCOCCI WITH A 2 WEEK COURSE OF CEFTRIAXONE FOLLOWED BY ORAL AMOXICILLIN
    RODRIGUEZ, JFG
    PREGO, JAM
    GOMEZ, DD
    [J]. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 1992, 11 (10) : 952 - 953
  • [4] SHORT-COURSE TREATMENT OF PENICILLIN-SUSCEPTIBLE VIRIDANS STREPTOCOCCAL INFECTIVE ENDOCARDITIS WITH PENICILLIN AND GENTAMICIN
    ROBERTS, SA
    LANG, SDR
    ELLISPEGLER, RB
    [J]. INFECTIOUS DISEASES IN CLINICAL PRACTICE, 1993, 2 (03) : 191 - 194
  • [5] EFFECT OF GENTAMICIN DOSING INTERVAL ON THERAPY OF VIRIDANS STREPTOCOCCAL EXPERIMENTAL ENDOCARDITIS WITH GENTAMICIN PLUS PENICILLIN
    GAVALDA, J
    PAHISSA, A
    ALMIRANTE, B
    LAGUARDA, M
    CRESPO, E
    POU, L
    FERNANDEZ, F
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1995, 39 (09) : 2098 - 2103
  • [6] Ceftriaxone once daily for four weeks vs ceftriaxone plus gentamicin for two weeks for the treatment of penicillin-susceptible streptococcal endocarditis.
    Sexton, D
    Tenenbaum, M
    Wilson, W
    Steckelberg, J
    Tice, A
    Gilbert, D
    Dismukes, W
    Drew, R
    Durack, D
    [J]. CLINICAL INFECTIOUS DISEASES, 1996, 23 (04) : 157 - 157
  • [7] ABSENCE OF THE PARADOXICAL EFFECT WHEN DETERMINING THE BACTERICIDAL ACTIVITY OF PENICILLIN AGAINST PENICILLIN-SUSCEPTIBLE STRAINS OF VIRIDANS GROUP STREPTOCOCCI
    MOODY, JA
    STEWARTWIGGLESWORTH, S
    WOOLFREY, BF
    [J]. CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL, 1992, 51 (05): : 763 - 772
  • [8] Comparative study of treatment with penicillin, ceftriaxone, trovafloxacin, quinupristin-dalfopristin and vancomycin in experimental endocarditis due to penicillin- and ceftriaxone-resistant Streptococcus pneumoniae
    Fornas, FL
    García, FM
    Salmeron, JP
    Conesa, DR
    Sanchez, RC
    Alberola, AG
    Gómez, JR
    Gómez, JG
    Chávarri, MV
    [J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2001, 47 (05) : 623 - 629
  • [9] Influence of gentamicin dosing interval on the efficacy of penicillin-containing regimens in experimental Enterococcus faecalis endocarditis
    Marangos, MN
    Nicolau, DP
    Quintiliani, R
    Nightingale, CH
    [J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1997, 39 (04) : 519 - 522
  • [10] Glycopeptides in monotherapy or combined with gentamycin in the treatment of experimental endocarditis due to penicillin-resistant viridans-group streptococci (VGS)
    Miro, J. M.
    Garcia de la Maria, C.
    Armero, Y.
    Moreno, A.
    Almela, M.
    Del Rio, A.
    Mestres, C. A.
    Jimenez de Anta, M. T.
    Gatell, J. M.
    Marco, F.
    [J]. CLINICAL RESEARCH IN CARDIOLOGY, 2007, 96 (06) : 415 - 416
12